Phloroglucinol Impurity 58 CAS 221652-95-5
| CAS No. | 221652-95-5 |
| Molecular Formula | C12H8O5 |
| Molecular Weight | 232.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Phloroglucinol Impurity 58 (CAS 221652-95-5) is a high-purity analytical reference standard with the molecular formula C12H8O5 and a molecular weight of 232.19 g/mol.
The molecular framework of Phloroglucinol Impurity 58 (C12H8O5) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H8O5 |
| Molecular Weight | 232.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2020 |
Related Phloroglucinol Standards
- Phloroglucinol impurity 44 (CAS 23957-21-3)
- Phloroglucinol Dihydrate EP Impurity D (CAS 491-45-2)
- Phloroglucinol Impurity 71 (CAS 112221-63-3)
- Phloroglucinol Impurity 72 (CAS 121034-97-7)
- Phloroglucinol Impurity 73 (CAS 112221-65-5)
- Phloroglucinol Impurity 25 (CAS 108-36-1)
- Phloroglucinol Aldehyde Triethyl Ether ; 100 MG (CAS 59652-88-9)
- Phloroglucinol Impurity 63 (CAS CATO-C4X-221763)
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