Phloroglucinol Impurity 73 CAS 112221-65-5
| CAS No. | 112221-65-5 |
| Molecular Formula | C12H10O5 |
| Molecular Weight | 234.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Phloroglucinol Impurity 73 (C12H10O5) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Phloroglucinol Impurity 73 (CAS 112221-65-5), a pharmacopoeial impurity reference standard (molecular formula C12H10O5, MW 234.20 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Phloroglucinol Impurity 73 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10O5 |
| Molecular Weight | 234.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
Related Phloroglucinol Standards
- Phloroglucinol Dihydrate EP Impurity D (CAS 491-45-2)
- Phloroglucinol Impurity 71 (CAS 112221-63-3)
- Phloroglucinol Impurity 72 (CAS 121034-97-7)
- Phloroglucinol Impurity 25 (CAS 108-36-1)
- Phloroglucinol Impurity 58 (CAS 221652-95-5)
- Phloroglucinol impurity 44 (CAS 23957-21-3)
- Phloroglucinol Aldehyde Triethyl Ether ; 100 MG (CAS 59652-88-9)
- Phloroglucinol Impurity 63 (CAS CATO-C4X-221763)
Recommended Standards
- Furfural Impurity 1 (CAS 7389-38-0)
- Lactitol Impurity 2 (CAS CATO-C4X-29472)
- Trimethyl Citrate (CAS 1587-20-8)
- Cabozantinib Impurity 28 (CAS 326-04-5)
- Tolterodine EP Impurity D Hydrochloride (CAS 1391053-65-8(free base))
- Cefuroxime Axetil Impurity 10 (CAS 64599-29-7)
- Roxithromycin Impurity 17 (CAS 74498-88-7)
- Loxoprofen impurity 89 (CAS CATO-C4X-148889)
- Copper compound with tin (1:1) (CAS 11099-34-6)
- 1-(P-tolyl)pentan-2-one (CAS 105994-83-0)
- 4-Chloro-8-methoxy-3-methylquinoline (CAS 39593-11-8)
- Isopropyl 2-amino-4-(4-(sec-butyl)phenyl)thiophene-3-carboxylate (CAS 351157-00-1)
- 2-Ethynyl-5-methoxypyrazine (CAS 1374115-62-4)
- Insulin Degludec Impurity 12 (CAS CATO-C4X-215712)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com