Phloroglucinol impurity 44 CAS 23957-21-3
| CAS No. | 23957-21-3 |
| Molecular Formula | C8H10BrNO2 |
| Molecular Weight | 232.07 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Phloroglucinol impurity 44 (CAS 23957-21-3, C8H10BrNO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C8H10BrNO2, Phloroglucinol impurity 44 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 232.07 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Phloroglucinol impurity 44 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H10BrNO2 |
| Molecular Weight | 232.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Phloroglucinol Standards
- Phloroglucinol Impurity 58 (CAS 221652-95-5)
- Phloroglucinol Dihydrate EP Impurity D (CAS 491-45-2)
- Phloroglucinol Impurity 71 (CAS 112221-63-3)
- Phloroglucinol Impurity 72 (CAS 121034-97-7)
- Phloroglucinol Impurity 73 (CAS 112221-65-5)
- Phloroglucinol Impurity 25 (CAS 108-36-1)
- Phloroglucinol Aldehyde Triethyl Ether ; 100 MG (CAS 59652-88-9)
- Phloroglucinol Impurity 63 (CAS CATO-C4X-221763)
Recommended Standards
- 87-48-9 5-Bromoisatin 5-Bromoindoline-2,3-dione 1H-Indole-2,3-dione, 5-bromo- (9CI) Indole-2,3-dione, 5-bromo- 5-21-10-00264 (Beilstein Handbook Reference) BRN 0383760 5-Bromisatin [Czech] 5-Bromoindole-2,3-dione EINECS 201-747-7 Isatin, 5-bromo- NSC 4980 5-Bromisatin (CAS 87-48-9)
- Tetrabenazine Impurity 44 (CAS 1637279-07-2)
- 6-Bromo-2,3-indolinedione 6-Bromoindole-2,3-dione 6-Bromoisatin 6326-79-0 B2424 (CAS 6326-79-0)
- 2,2,3,3,4,4,5,5-Octafluoro-1-pentanol (CAS 355-80-6)
- Chenodeoxycholic Acid Impurity 4 (CAS CATO-C4X-15834)
- Iloprost Impurity 4 (CAS CATO-C4X-32024)
- Dotinurad Impurity 58 (CAS CATO-C4X-249458)
- 8-(tert-Butoxycarbonyl)-5-oxa-8-azaspiro[3.5]nonane-2-carboxylic acid (CAS 1250999-58-6)
- 2-Bromo-3,4-difluorophenol (CAS 1376335-05-5)
- 2-Amino-7-chlorobenzo[d]thiazol-4-ol (CAS 98273-04-2)
- Tert-butyl7-oxo-1-azaspiro[3.5]nonane-1-carboxylate (CAS 2306264-15-1)
- 1-(4-Fluorobenzyl)piperidine-3-carboxylic acid (CAS 832737-45-8)
- Sulfluramid (CAS 4151-50-2)
- Galanin-Like Peptide (rat) trifluoroacetate salt (CAS 245114-97-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com