Phloroglucinol Dihydrate EP Impurity D CAS 491-45-2
| CAS No. | 491-45-2 |
| Molecular Formula | C12H10O5 |
| Molecular Weight | 234.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Phloroglucinol Dihydrate EP Impurity D (CAS 491-45-2) is a certified pharmaceutical impurity reference standard with the molecular formula C12H10O5 and a molecular weight of 234.20 g/mol.
Phloroglucinol Dihydrate EP Impurity D (C12H10O5) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Phloroglucinol Dihydrate EP Impurity D under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H10O5 |
| Molecular Weight | 234.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Phloroglucinol Standards
- Phloroglucinol Impurity 71 (CAS 112221-63-3)
- Phloroglucinol Impurity 72 (CAS 121034-97-7)
- Phloroglucinol Impurity 73 (CAS 112221-65-5)
- Phloroglucinol Impurity 25 (CAS 108-36-1)
- Phloroglucinol Impurity 58 (CAS 221652-95-5)
- Phloroglucinol impurity 44 (CAS 23957-21-3)
- Phloroglucinol Aldehyde Triethyl Ether ; 100 MG (CAS 59652-88-9)
- Phloroglucinol Impurity 63 (CAS CATO-C4X-221763)
Recommended Standards
- Cabozantinib Impurity 28 (CAS 326-04-5)
- Sodium Cromoglicate Impurity 10 (CAS 50521-64-7)
- Riluzole Impurity 8 (CAS 1391054-04-8)
- Riluzole Impurity 5 (CAS 235101-36-7)
- Rimegepant Impurity 113 (CAS 1452167-10-0)
- Lenalidomide Impurity 49 (CAS CATO-C4X-190349)
- Levofloxacin Impurity 9 (CAS 1797099-76-3)
- Xanthine-13C-15N2 (CAS 1262670-81-4)
- 1-(4-Chloro-3-fluorophenyl)propan-2-one (CAS 206362-95-0)
- Riociguat Impurity 24 (CAS 256376-62-2)
- 5-(4-Butoxyphenyl)-7-methyl-2-(p-tolyl)-3H-benzo[e][1,2,4]triazepine (CAS 444153-21-3)
- 2-(2-(5-Bromo-1H-indol-3-yl)-2-oxoacetamido)-3-phenylpropanoic acid (CAS 97500-76-0)
- Ethyl 7-amino-3-chlorothieno[2,3-b]pyrazine-6-carboxylate (CAS 181284-02-6)
- Semaglutide Impurity 10 (CAS CATO-C4X-222610)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com