Posaconazole Impurity 1 CAS 2243786-01-6
| CAS No. | 2243786-01-6 |
| Molecular Formula | C30H35N5O3 |
| Molecular Weight | 513.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Posaconazole Impurity 1 (CAS 2243786-01-6, C30H35N5O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Posaconazole Impurity 1 (C30H35N5O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 16.0, corresponding to approximately 16 ring(s) or double-bond equivalent(s). With a molecular weight of 513.63 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Posaconazole Impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C30H35N5O3 |
| Molecular Weight | 513.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 5 |
Related Posaconazole Standards
- Posaconazole Impurity 2 (CAS 2243786-00-5)
- Posaconazole Impurity 3 (CAS 2243786-02-7)
- Posaconazole Impurity 4 (CAS 184177-83-1)
- Posaconazole Impurity 159 (CAS CATO-C4X-1208159)
- Posaconazole Impurity 58 (CAS CATO-C4X-120858)
- Posaconazole impurity 249 (CAS CATO-C4X-1208249)
- Posaconazole Impurity 266 (CAS CATO-C4X-1208266)
- Posaconazole Impurity 30 (CAS CATO-C4X-120830)
Recommended Standards
- Ibrutinib Impurity 162 (CAS CATO-C4X-1064162)
- Valsartan Impurity 57 (CAS 1353844-77-5)
- Pyridine, 2,6-bis[[2-[(4S)-4,5-dihydro-4-(1-methylethyl)-2-oxazolyl]phenoxy]methyl]- (CAS 850533-59-4)
- N-(1-(3-methoxypropyl)-2-oxo-1,2-dihydrobenzo[cd]indol-6-yl)-1-(thiophen-2-ylsulfonyl)piperidine-2-carboxamide (CAS 2417772-39-3)
- Sulpiride impurity 15 (CAS 77718-16-2)
- Lusutrombopag Impurity 55 (CAS CATO-C4X-208455)
- Apalutamide Impurity 6 (CAS 1332391-11-3)
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- 3-(tert-Butyl)-2-hydroxy-5-nitrobenzaldehyde (CAS 72607-35-3)
- 4-Bromo-2-nitro-5-(pentyloxy)aniline (CAS 1255574-52-7)
- 1-(4-Bromophenyl)-5-oxopyrrolidine-3-carbonitrile (CAS 1017458-55-7)
- 2-((3-Methoxyphenyl)amino)-2-(thiophen-2-yl)acetic acid (CAS 725253-16-7)
- 2512AE 39928-72-8 5-(Chloromethyl)dihydrofuran-2(3H)-one C5H7ClO2 (CAS 39928-72-8)
- Protein Kinase C (alpha) Peptide (CAS 159939-84-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com