Posaconazole Impurity 266 CAS CATO-C4X-1208266
| CAS No. | CATO-C4X-1208266 |
| Molecular Formula | C29H37N5O3 |
| Molecular Weight | 503.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Posaconazole Impurity 266 (CAS CATO-C4X-1208266), a pharmacopoeial impurity reference standard (molecular formula C29H37N5O3, MW 503.64 g/mol) used for the identification and quantification of trace impurities in APIs.
Posaconazole Impurity 266 (C29H37N5O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C29H37N5O3 |
| Molecular Weight | 503.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Posaconazole Standards
- Posaconazole Impurity 30 (CAS CATO-C4X-120830)
- Posaconazole Impurity 5 (CAS 345217-02-9)
- Posaconazole Impurity 87 (CAS CATO-C4X-120887)
- Posaconazole impurity 249 (CAS CATO-C4X-1208249)
- Posaconazole Impurity 261 (CAS 2376724-98-8)
- Posaconazole Impurity 34 (CAS CATO-C4X-120834)
- Posaconazole Impurity 159 (CAS CATO-C4X-1208159)
- Posaconazole Impurity 58 (CAS CATO-C4X-120858)
Recommended Standards
- Palbociclib Impurity 85 (CAS CATO-C4X-112585)
- Palbociclib Impurity 79 (CAS CATO-C4X-112579)
- Palbociclib Impurity 103 (CAS 2270982-31-3)
- Ibrutinib Impurity 127 (CAS CATO-C4X-1064127)
- Temozolomide Impurity 2 (CAS 287964-59-4)
- Betamethasone impurity 45 (CAS 1215899-29-8)
- Probucol Impurity 16 (CAS 2093160-06-4)
- 2-(3-Chloro-2-methoxy-5-methylphenyl)-4-methylpyrrolidine (CAS 603068-55-9)
- Benzyl N-[1-(aminomethyl)cyclopropyl]carbamate (CAS 1439909-08-6)
- N-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropanecarboxamide (CAS 1031747-40-6)
- (S)-1-benzylpiperidin-3-amine dihydrochloride (CAS 307532-02-1)
- Methyl 2-(methylthio)acetimidate (CAS 83353-53-1)
- 2-(Isopropylamino)-2-methylpropanenitrile (CAS 16256-47-6)
- Semaglutide impurity 73 (CAS CATO-C4X-222673)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com