Atorvastatin Impurity 77 CAS 2299304-89-3
| CAS No. | 2299304-89-3 |
| Molecular Formula | C24H44N2O7 |
| Molecular Weight | 472.62 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Atorvastatin Impurity 77.
Atorvastatin Impurity 77 (CAS 2299304-89-3) is a certified pharmaceutical impurity reference standard with the molecular formula C24H44N2O7 and a molecular weight of 472.62 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Atorvastatin Impurity 77 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 472.62 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Atorvastatin Impurity 77 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H44N2O7 |
| Molecular Weight | 472.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Nitrogen Atoms | 2 |
Related Atorvastatin Standards
- Atorvastatin Impurity 125 (CAS 1821498-27-4)
- Atorvastatin Calcium EP Impurity D (CAS 873950-19-7)
- Atorvastatin Impurity 86 (CAS 1046118-44-8)
- Atorvastatin Impurity 99 (CAS CATO-C4X-113299)
- Atorvastatin Impurity 27 (CAS 693793-82-7)
- Atorvastatin EP Impurity D (CAS 148146-51-4)
- Atorvastatin Impurity 95 (CAS 442851-50-5)
- Atorvastatin Impurity 103 (CAS 1797905-42-0)
Recommended Standards
- 4-(5-(Benzylthio)-4-ethyl-4H-1,2,4-triazol-3-yl)-1-((4-methoxyphenyl)sulfonyl)piperidine (CAS 672950-67-3)
- Verapamil Impurity 43 (CAS 94219-84-8)
- 3 -O-tert-Butyl-2-deoxymugineic Acid tert-Butyl Diethyl Ester (CAS 958350-41-9)
- Oclacitinib impurity 1 (CAS CATO-C4X-30181)
- Maropitant Impurity 14 (CAS CATO-C4X-250814)
- Rivaroxaban Impurity 205 (CAS CATO-C4X-1090205)
- Amlodipine Besylate EP Impurity A (CAS 88150-62-3)
- Ethyl 2-hydrazinylpyrimidine-5-carboxylate (CAS 1314937-96-6)
- 4,5-Difluoro-2-nitroaniline (CAS 78056-39-0)
- CHOLESTAN-3β, 5α-DIOL-6-ONE (CAS 13027-33-3)
- (5-(4-Chlorophenyl)-1H-1,2,4-triazol-3-yl)(4-fluorophenyl)methanamine (CAS 1707566-70-8)
- 8-(Tert-butyl)-2-azaspiro[4.5]decane-1,3-dione (CAS 183120-06-1)
- N1-Cyclopropyl-N1-(1-(pyridin-2-yl)ethyl)ethane-1,2-diamine (CAS 1353986-61-4)
- Semaglutide impurity 44 (CAS CATO-C4X-222644)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com