Atorvastatin Impurity 99 CAS CATO-C4X-113299
| CAS No. | CATO-C4X-113299 |
| Molecular Formula | C26H23FN2O4 |
| Molecular Weight | 446.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Atorvastatin Impurity 99 (C26H23FN2O4) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 16.0, corresponding to approximately 16 ring(s) or double-bond equivalent(s). With a molecular weight of 446.47 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Atorvastatin Impurity 99 (CAS CATO-C4X-113299, C26H23FN2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Atorvastatin Impurity 99 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H23FN2O4 |
| Molecular Weight | 446.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Atorvastatin Standards
- Atorvastatin Calcium EP Impurity D (CAS 873950-19-7)
- Atorvastatin Impurity 86 (CAS 1046118-44-8)
- Atorvastatin Impurity 27 (CAS 693793-82-7)
- Atorvastatin EP Impurity D (CAS 148146-51-4)
- Atorvastatin Impurity 77 (CAS 2299304-89-3)
- Atorvastatin Impurity 103 (CAS 1797905-42-0)
- Atorvastatin Oxirane Impurity (CAS 1246818-88-1)
- Atorvastatin Impurity 82 (CAS 125971-96-2)
Recommended Standards
- Apremilast impurity 8 (CAS CATO-C4X-10098)
- Triamcinolone Acetonide Impurity 44 (CAS CATO-C4X-132644)
- Apremilast Impurity 75 (CAS CATO-C4X-100975)
- Ampiroxicam (CAS 99464-64-9)
- Nafamostat impurity 99 (CAS CATO-C4X-133299)
- Posaconazole Impurity 166 (CAS 1631169-28-2)
- Procaterol Impurity 21 (CAS CATO-C4X-181021)
- Atomoxetine Chloro Impurity (CAS 114446-47-8)
- tert-Butyl N-(4-aminophenyl)-N-methylcarbamate (CAS 1092522-02-5)
- Methyl 4-allyl-5-(benzyloxy)-2-methoxybenzoate (CAS 359844-07-8)
- Tert-butyl n-(2-aminoethyl)-n-cyclopropylcarbamate (CAS 1247174-47-5)
- 8-Bromo-6-methyl-1,2,3,4-tetrahydroquinoline (CAS 887749-24-8)
- 2-(4-Dimethylaminophenyl)-1,3-thiazole-4-carboxylic acid (CAS 955400-50-7)
- Neuroendocrine Regulatory Peptide-1 (rat) (CAS 954420-51-0)
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