Atorvastatin Impurity 125 CAS 1821498-27-4
| CAS No. | 1821498-27-4 |
| Molecular Formula | C27H30FNO6 |
| Molecular Weight | 483.53 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Atorvastatin Impurity 125 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Atorvastatin Impurity 125 (CAS 1821498-27-4, C27H30FNO6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Atorvastatin Impurity 125 (C27H30FNO6) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Atorvastatin Impurity 125 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H30FNO6 |
| Molecular Weight | 483.53 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Atorvastatin Standards
- Atorvastatin Impurity 77 (CAS 2299304-89-3)
- Atorvastatin Calcium EP Impurity D (CAS 873950-19-7)
- Atorvastatin Impurity 86 (CAS 1046118-44-8)
- Atorvastatin Impurity 99 (CAS CATO-C4X-113299)
- Atorvastatin Impurity 95 (CAS 442851-50-5)
- Atorvastatin Impurity 27 (CAS 693793-82-7)
- Atorvastatin EP Impurity D (CAS 148146-51-4)
- Atorvastatin Impurity 146 (CAS CATO-C4X-1132146)
Recommended Standards
- rel-(4R,5S)-2,4,5-Trimethyl-4,5-dihydrothiazole (CAS 23236-43-3)
- Roxadustat Impurity 7 (CAS 1455091-06-1)
- Ethyl 2-(2-((3-cyano-6-methyl-4-(trifluoromethyl)pyridin-2-yl)thio)acetamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (CAS 445383-14-2)
- 2-(Benzo[d][1,3]dioxol-5-yl)-1-oxo-N-(pyridin-4-ylmethyl)-3-(thiophen-3-yl)-1,2,3,4-tetrahydroisoquinoline-4-carboxamide (CAS 1023500-67-5)
- Rebamipide Impurity 35 HCl (CAS CATO-C4X-152335)
- Ribavirin Impurity 41 (CAS 905-14-6)
- N-Nitroso Risperidone Impurity 48 (CAS CATO-C4X-111148)
- 5-Bromo-2-(methylsulfanyl)benzoic acid (CAS 62176-40-3)
- 5,6-Dichloro-3-(3-methoxypropyl)pyrimidine-2,4(1H,3H)-dione (CAS 1710846-97-1)
- 5-Bromo-7-chloro-3-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-c]pyridine (CAS 1305324-83-7)
- 6-Methoxy-2,3-dihydro-1h-indene-5-carboxylic acid (CAS 77366-70-2)
- 5-Fluoro-2-(phenylsulfonyl)-1H-indole (CAS 1555519-77-1)
- 3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[4,5-b]pyridine (CAS 1257554-02-1)
- Peptide Impurity 41 (CAS CATO-CPTD788841)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com