Benzocaine Impurity 6 CAS 23437-10-7
| CAS No. | 23437-10-7 |
| Molecular Formula | C18H17NO5 |
| Molecular Weight | 327.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Benzocaine Impurity 6.
As a process- or degradation-related impurity, Benzocaine Impurity 6 (CAS 23437-10-7, C18H17NO5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Benzocaine Impurity 6 (C18H17NO5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Benzocaine Impurity 6 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H17NO5 |
| Molecular Weight | 327.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 1 |
Related Benzocaine Standards
- Benzocaine N-D-Fructoside (CAS 78306-17-9)
- Benzocaine-N-glucoside (CAS 28315-50-6)
- Benzocaine Impurity 31 (CAS 71134-95-7)
- Benzocaine impurity 32 (CAS 5338-44-3)
- Benzocaine-13C6 (CAS 1391054-61-7)
- Benzocaine EP Impurity D (CAS 1333-08-0)
- Benzocaine EP Impurity C (CAS 582-33-2)
- Benzocaine EP Impurity H (CAS 619-45-4)
Recommended Standards
- Tranilast Impurity 2 (CAS 91920-58-0)
- Pemafibrate Impurity 49 (CAS CATO-C4X-290349)
- Tranilast Impurity 1 (CAS 70806-55-2)
- Tranilast (CAS 53902-12-8)
- Cephalexin Impurity 41 (CAS CATO-C4X-126141)
- Clomifene Citrate EP Impurity D (CAS 1391054-64-0)
- Urapidil Impurity 19 (CAS 2287518-97-0)
- N-Nitroso Meclofenamic Acid (CAS CATO-C4X-29681)
- (3AS,4R,6aR)-2,2-dimethyl-3a,6a-dihydro-4H-cyclopenta[d][1,3]dioxol-4-amine (CAS 71773-15-4)
- 2-[(2-Methylprop-2-en-1-yl)oxy]benzaldehyde (CAS 38002-87-8)
- 4-(4-Methoxyphenyl)-2-[3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazole (CAS 955976-85-9)
- (11aR)-N,N-Dicyclohexyl-10,11,12,13-tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-5-amine (CAS 500997-68-2)
- Hydroxymethyl Coumarin Impurity 7 (CAS 52751-48-1)
- Cholecystokinin Octapeptide (1-3) (desulfated) H-Asp-Tyr-Met-OH (CAS 121880-94-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com