Ticagrelor Impurity 15 CAS 2376278-72-5
| CAS No. | 2376278-72-5 |
| Molecular Formula | C10H19NO4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Ticagrelor Impurity 15 (C10H19NO4C4H6O6) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Ticagrelor Impurity 15 (CAS 2376278-72-5, C10H19NO4C4H6O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Ticagrelor Impurity 15 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H19NO4 C4H6O6 |
| Molecular Weight | 367.35 g/mol |
| Appearance | White to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1999 |
| Nitrogen Atoms | 1 |
Related Ticagrelor Standards
- Ticagrelor Impurity N40 (CAS 1006376-60-8)
- Ticagrelor Impurity 88 (CAS 1006376-61-9)
- Ticagrelor Impurity 152 (CAS 1006376-62-0)
- Ticagrelor Impurity 121 (CAS 1006614-49-8)
- Ticagrelor impurity 84（trans） (CAS 1006614-51-2)
- Ticagrelor Impurity 113 (CAS 1156575-52-8)
- Ticagrelor impurity 161 (CAS 1157692-93-7)
- Ticagrelor Impurity 168 (CAS 1207276-00-3(free base))
Recommended Standards
- Sodium Fusidate EP Impurity D (CAS CATO-C4X-11974)
- Lornoxicam Impurity 43 (CAS CATO-C4X-201643)
- Palbociclib Impurity 102 (CAS CATO-C4X-1125102)
- 2-Chloro-N-(cyano-2-thienylmethyl)acetamide (CAS 263137-41-3)
- (1-(Tert-butyl)-1H-pyrazol-4-yl)(1-hydroxynaphthalen-2-yl)methanone (CAS 955976-51-9)
- Tert-butyl 3-[4-(aminomethyl)-1h-1,2,3-triazol-1-yl]pyrrolidine-1-carboxylate (CAS 1437385-23-3)
- 5,8-Dioxa-10-azadispiro[2.0.4.3]undecane (CAS 129321-60-4)
- Lemborexant Impurity 48 (CAS CATO-C4X-304248)
- (3R,4S)-1-(tert-butoxycarbonyl)-4-(3-ethoxy-4-methoxyphenyl)pyrrolidine-3-carboxylic acid (CAS 2227694-79-1)
- Liraglutide(3-31)TFA Salt (CAS CATO-C4X-19921)
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