Agomelatine Impurity 25 CAS 6836-22-2
| CAS No. | 6836-22-2 |
| Molecular Formula | C13H12O3 |
| Molecular Weight | 216.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Agomelatine Impurity 25 (C13H12O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Agomelatine Impurity 25 (CAS 6836-22-2) is a certified pharmaceutical impurity reference standard with the molecular formula C13H12O3 and a molecular weight of 216.23 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Agomelatine Impurity 25 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H12O3 |
| Molecular Weight | 216.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Related Agomelatine Standards
- Agomelatine Impurity 11 (CAS 138113-07-2)
- Agomelatine Impurity 43 (CAS CATO-C4X-110843)
- Agomelatine Impurity 10 (CAS 20176-04-9)
- Agomelatine Impurity 34 (CAS 27533-69-3)
- Agomelatine Impurity 17 (CAS 92041-01-5)
- Agomelatine Impurity 44 (CAS 55917-07-2)
- Agomelatine Impurity 26 (CAS 945853-23-6)
- Agomelatine Impurity 27 (CAS CATO-C4X-110827)
Recommended Standards
- Pitavastatin Impurity 105 (CAS CATO-C4X-1037105)
- Naproxen EP Impurity I (CAS 23981-47-7)
- 3-(3-Methoxyphenoxy)phenol (CAS 122283-28-7)
- Naproxen EP Impurity A (CAS 52079-10-4)
- Sunitinib Impurity 73 (CAS CATO-C4X-133373)
- Loratadine EP Impurity C (CAS 165739-83-3)
- Labetalol Impurity 46 (CAS CATO-C4X-246646)
- 2-(5,5-Dimethyl-2,4-dioxooxazolidin-3-yl)acetic acid (CAS 872806-40-1)
- Phenyl (4-(fluorosulfonyl)phenyl)carbamate (CAS 21315-97-9)
- 4-Chloro-5-(difluoromethyl)-3-methylpicolinic acid (CAS 1805379-45-6)
- 5-Chloro-2-methylpyrazolo[1,5-a]quinazoline (CAS 885525-06-4)
- Methyl 4-(benzyloxy)-2-hydroxybenzoate (CAS 5427-29-2)
- 5-Amino-2-cyclobutyloxazole-4-carbonitrile (CAS 909077-19-6)
- Insulin Degludec Impurity 7 (CAS CATO-C4X-21577)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com