Hydroxychloroquine Impurity 35 CAS CATO-C4X-183535
| CAS No. | CATO-C4X-183535 |
| Molecular Formula | C27H30Cl2N4O |
| Molecular Weight | 497.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Hydroxychloroquine Impurity 35 (CAS CATO-C4X-183535, C27H30Cl2N4O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C27H30Cl2N4O, Hydroxychloroquine Impurity 35 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 497.46 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Hydroxychloroquine Impurity 35 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H30Cl2N4O |
| Molecular Weight | 497.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Hydroxychloroquine Standards
- Hydroxychloroquine Impurity 74 (CAS 2411340-32-2)
- Hydroxychloroquine Impurity 43 (CAS CATO-C4X-183543)
- Hydroxychloroquine Impurity 39 (CAS CATO-C4X-183539)
- Hydroxychloroquine impurity 82 (CAS CATO-C4X-183582)
- Hydroxychloroquine Impurity 37 (CAS CATO-C4X-183537)
- Hydroxychloroquine Impurity 44 (CAS CATO-C4X-183544)
- Hydroxychloroquine Impurity 41 (CAS CATO-C4X-183541)
- Hydroxychloroquine Impurity 42 (CAS CATO-C4X-183542)
Recommended Standards
- Methotrexate impurity 51 (CAS CATO-C4X-115451)
- 4-Nitro-Z-Gly-Trp-Gly-OH (M-1595.0050) (CAS 64792-79-6)
- 2-(1-(4-Ethoxybenzoyl)-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 1007998-55-1)
- 2,3,4,5,6-Pentafluoro-N-(4-hydroxy-3-(phenylthio)naphthalen-1-yl)benzenesulfonamide (CAS 1809581-87-0)
- Acotiamide Impurity 20 (CAS CATO-C4X-111420)
- Nabumetone Impurity 18 (CAS 701270-26-0)
- Sorafenib impurity 66 (CAS CATO-C4X-112466)
- Fosaprepitant impurity 57（S,R,R） (CAS CATO-C4X-116857)
- 6-Bromo-3,4-dihydrospiro[benzo[b][1,4]oxazine-2,1'-cyclopropane] (CAS 1291094-46-6)
- 3-(5-{[(4-Methylphenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)propanoic acid (CAS 1142202-66-1)
- 8-Chloro-6-fluoro-3,4-dihydronaphthalen-2(1H)-one (CAS 1337859-03-6)
- 6-Methyl-5h-[1,2,4]triazino[5,6-b]indole-3-thiol (CAS 83515-26-8)
- Ac-Tyr-Val-Ala-Asp-aldehyde (pseudo acid) (CAS 143313-51-3)
- Liraglutide Impurity 30 (CAS CATO-C4X-199230)
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