Entacapone Impurity N5 CAS 2426-86-0
| CAS No. | 2426-86-0 |
| Molecular Formula | C8H7NO5 |
| Molecular Weight | 197.14 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Entacapone Impurity N5.
As a process- or degradation-related impurity, Entacapone Impurity N5 (CAS 2426-86-0, C8H7NO5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C8H7NO5, Entacapone Impurity N5 contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 197.14 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Entacapone Impurity N5 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H7NO5 |
| Molecular Weight | 197.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Entacapone Standards
- Entacapone Impurity 25 (CAS 6635-20-7)
- Entacapone Impurity 28 (CAS 2450-26-2)
- Entacapone Impurity 29 (CAS 2454-72-0)
- Entacapone Impurity 31 (CAS 80547-69-9)
- Entacapone Impurity 32 (CAS CATO-C4X-162932)
- Entacapone Impurity 33 (CAS 144683-49-8)
- Entacapone Impurity 34 (CAS 144683-48-7)
- Entacapone EP Impurity E (CAS 7659-29-2)
Recommended Standards
- Gefitinib Impurity N18 (CAS 58749-47-6)
- 2-Hydroxy-5-nitro-m-anisaldehyde (CAS 17028-61-4)
- 2-hydroxy-3-methoxy-4-nitrobenzaldehyde (CAS 20041-61-6)
- 3-Hydroxy-4-methoxy-2-nitrobenzaldehyde (CAS 6284-92-0)
- Pitolisant impurity 30 (CAS CATO-C4X-252030)
- Mianserin Impurity 81 (CAS 73771-03-6)
- Ataluren Impurity 6 (CAS 775304-58-0)
- 4-Cyano-2-fluoro-6-methylbenzoic acid (CAS 1805051-09-5)
- H-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-OH (CAS 6934-38-9)
- Dimethyl 4-Oxocyclopentane-1,2-dicarboxylate (CAS 6453-07-2)
- Benzothiophene 1,1-Dioxide (CAS 825-44-5)
- (4-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(2,4-difluorophenyl)methanone (CAS 898758-43-5)
- Ethyl 2-(dimethylamino)pyrimidine-5-carboxylate (CAS 64224-68-6)
- Peptide Impurity 12 (CAS CATO-CPTD788812)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com