Tolvaptan Impurity 76 CAS 2458812-63-8
| CAS No. | 2458812-63-8 |
| Molecular Formula | C24H22N2O4 |
| Molecular Weight | 402.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Tolvaptan Impurity 76 (C24H22N2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Tolvaptan Impurity 76 (CAS 2458812-63-8), a pharmacopoeial impurity reference standard (molecular formula C24H22N2O4, MW 402.44 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Tolvaptan Impurity 76 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H22N2O4 |
| Molecular Weight | 402.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Nitrogen Atoms | 2 |
Related Tolvaptan Standards
- Tolvaptan Impurity 64 (CAS CATO-C4X-195564)
- Tolvaptan Impurity 22 (CAS CATO-C4X-195522)
- Tolvaptan Impurity 6 (CAS 137976-61-5)
- Tolvaptan Impurity 129 (CAS 1448365-49-8)
- Tolvaptan Impurity 72 (CAS CATO-C4X-195572)
- Tolvaptan Impurity 118 (CAS CATO-C4X-1955118)
- Tolvaptan Impurity 124 (CAS CATO-C4X-1955124)
- Tolvaptan Impurity 89 (CAS 137977-65-2)
Recommended Standards
- Trimebutine Impurity 10 (CAS CATO-C4X-185810)
- Polmacoxib Impurity 2 (CAS CATO-C4X-20412)
- Ticarcillin Impurity 9 (CAS CATO-C4X-17639)
- Drotaverin Impurity 45 (CAS 855199-57-4)
- Mianserin impurity 55 (CAS CATO-C4X-136955)
- Sitafloxacin impurity 72 (CAS CATO-C4X-115572)
- Apixaban Impurity 7 (CAS 1777781-49-3)
- 4-(1-Aminoethyl)-2-bromophenol (CAS 1337139-52-2)
- 7-Bromo-8-methylpyrido[2,3-b]pyrazine (CAS 116605-69-7)
- N-(3-Bromobenzyl)-2-chloro-N-cyclopropylacetamide (CAS 1176625-60-7)
- N1,N3-bis(2-(1H-indol-3-yl)ethyl)-2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)malonamide (CAS 478258-07-0)
- 4-(4-Methoxynaphthalen-1-yl)thiazole-2-carbaldehyde (CAS 383142-30-1)
- 2-(Cyclopropylmethoxy)-6-fluoropyridine (CAS 1224719-36-1)
- Semaglutide Impurity 16 (CAS CATO-C4X-222616)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com