Apremilast Impurity 130 CAS 2487573-03-3

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.2487573-03-3
Molecular FormulaC22H24N2O7S
Molecular Weight460.50 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Apremilast Impurity 130 CAS 2487573-03-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 460.50 g/mol gives Apremilast Impurity 130 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Apremilast Impurity 130 (CAS 2487573-03-3) is a certified pharmaceutical impurity reference standard with the molecular formula C22H24N2O7S and a molecular weight of 460.50 g/mol.

Based on its molecular formula C22H24N2O7S, Apremilast Impurity 130 contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 460.50 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Apremilast Impurity 130 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC22H24N2O7S
Molecular Weight460.50 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2000
Nitrogen Atoms2
Sulfur Atoms1

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