Clobetasone 17-Butyrate CAS 25122-57-0
| CAS No. | 25122-57-0 |
| Molecular Formula | C26H32ClFO5 |
| Molecular Weight | 478.98 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Clobetasone 17-Butyrate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Clobetasone 17-Butyrate (CAS 25122-57-0) is a high-purity analytical reference standard with the molecular formula C26H32ClFO5 and a molecular weight of 478.98 g/mol.
Based on its molecular formula C26H32ClFO5, Clobetasone 17-Butyrate contains a steroid core, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 478.98 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C26H32ClFO5 |
| Molecular Weight | 478.98 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | F/Cl-containing |
Related Clobetasone Standards
- Clobetasone Butyrate EP Impurity I (CAS 639817-47-3)
- Clobetasone Butyrate EP Impurity F (CAS 25120-98-3)
- Clobetasone butyrate EP Impurity E (CAS 639817-48-4)
- Clobetasone butyrate EP Impurity C (CAS 639817-49-5)
- Clobetasone Butyrate EP Impurity H (CAS 25122-56-9)
- Clobetasone butyrate EP Impurity G (CAS CATO-C4X-35394)
- Clobetasone Butyrate Impurity 7 (CAS CATO-C4X-35397)
- Clobetasone Butyrate EP Impurity A (CAS 54063-32-0)
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