Rivaroxaban Impurity N2 CAS 25413-76-7
| CAS No. | 25413-76-7 |
| Molecular Formula | C8H10N2O2 |
| Molecular Weight | 166.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C8H10N2O2, Rivaroxaban Impurity N2 contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 166.18 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Rivaroxaban Impurity N2 (CAS 25413-76-7, C8H10N2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Rivaroxaban Impurity N2 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H10N2O2 |
| Molecular Weight | 166.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Nitrogen Atoms | 2 |
Related Rivaroxaban Standards
- Rivaroxaban Impurity 47 (CAS 22576-65-4)
- Rivaroxaban Impurity 25 (CAS 2648-71-7)
- Rivaroxaban Impurity 135 (CAS 53935-71-0)
- Rivaroxaban Impurity 136 (CAS 36157-42-3)
- Rivaroxaban Impurity 21 (CAS 59337-89-2)
- Rivaroxaban EP Impurity F (CAS 24065-33-6)
- Rivaroxaban Impurity 90 (CAS 59614-95-8)
- Rivaroxaban Impurity 114 (CAS 22353-82-8)
Recommended Standards
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- N-methyl-N-(pyridin-4-yl)glycine (CAS 736913-58-9)
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- Neratinib Impurity 21 (CAS 1144516-15-3)
- Fluconazole Impurity 75 (CAS CATO-C4X-101975)
- 2-([1,1'-Biphenyl]-4-yl)-4,5-diphenylthiazole (CAS 1965304-79-3)
- N-Me-Ser-OH (CAS 2480-26-4)
- 4,4＇-Diaminobenzanilide (CAS 785-30-8)
- 2-(Bromoethynyl)furan (CAS 333952-15-1)
- N-(4-chlorophenyl)-6-oxo-1-(4-(trifluoromethyl)benzyl)-1,6-dihydropyridine-3-carboxamide (CAS 339008-67-2)
- N1,N1-diethyl-N2-(tetrahydrothiophen-3-yl)ethane-1,2-diamine (CAS 1019623-38-1)
- Tirzepatide Impurity 26 X TFA Salt (CAS CATO-C4X-324026)
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