Edoxaban Impurity 25 CAS 2605225-75-8
| CAS No. | 2605225-75-8 |
| Molecular Formula | C24H30ClN7O4S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Edoxaban Impurity 25.
Edoxaban Impurity 25 (CAS 2605225-75-8) is a certified pharmaceutical impurity reference standard with the molecular formula C24H30ClN7O4SC7H8O3S and a molecular weight of 720.26 g/mol.
Structurally, Edoxaban Impurity 25 (C24H30ClN7O4SC7H8O3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 16.0, corresponding to approximately 16 ring(s) or double-bond equivalent(s). With a molecular weight of 720.26 g/mol, it falls into the high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H30ClN7O4S C7H8O3S |
| Molecular Weight | 720.26 g/mol |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 7 |
| Sulfur Atoms | 2 |
Related Edoxaban Standards
- Edoxaban Impurity 73 (CAS 1057651-37-2)
- Edoxaban Impurity 7 (CAS 1072-98-6)
- Edoxaban Impurity 71 (CAS 1093351-29-1)
- Edoxaban Impurity N8 HCl (CAS 1190971-73-3)
- Edoxaban Impurity 47 (CAS 1210348-16-5)
- Edoxaban Impurity 74 (CAS 1210348-21-2)
- Edoxaban Impurity 20 (CAS 1210348-34-7)
- Edoxaban Tosylate Monohydrate (CAS 1229194-11-9)
Recommended Standards
- Nebivolol Impurity 3（RR,SS） (CAS 1360598-84-0)
- Flomoxef Impurity 41 (CAS CATO-C4X-138241)
- Pibrentasvir Impurity 1 (CAS CATO-C4X-28931)
- Metformin Impurity 27 (CAS 18240-93-2)
- (R)-2-amino-2-(2-chlorophenyl)ethan-1-ol (CAS 1212831-53-2)
- o-Tolyl 8-methyl-2-phenylquinoline-4-carboxylate (CAS 355421-34-0)
- 1H-Pyrazole-3-carboxylic acid, 4-ethyl-, hydrochloride (1:1) (CAS 2445794-88-5)
- 3-(2-Bromoimidazo[2,1-b]thiazol-6-yl)propanoic acid (CAS 1187884-13-4)
- Ticagrelor Impurity 150 (CAS 220349-80-4)
- MCH-Gene-Overprinted-Polypeptide-14 (rat) (H-4746.0500) (CAS 182917-44-8)
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