Sildenafil Impurity 21 CAS 268204-00-8
| CAS No. | 268204-00-8 |
| Molecular Formula | C9H16N4O |
| Molecular Weight | 196.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Sildenafil Impurity 21 (CAS 268204-00-8), a pharmacopoeial impurity reference standard (molecular formula C9H16N4O, MW 196.25 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C9H16N4O, Sildenafil Impurity 21 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 196.25 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Sildenafil Impurity 21 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H16N4O |
| Molecular Weight | 196.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
Related Sildenafil Standards
- Sildenafil Impurity 54 (CAS 133261-07-1)
- Sildenafil Impurity 30 (CAS 59259-90-4)
- Sildenafil Impurity 99 (CAS CATO-C4X-112899)
- Sildenafil Impurity 253 (CAS CATO-C4X-1128253)
- Sildenafil Impurity 45 (CAS 62871-12-9)
- Sildenafil Impurity 1 (CAS 42926-52-3)
- Sildenafil Impurity 56 (CAS CATO-C4X-112856)
- Sildenafil Impurity 274 (CAS 1358966-40-1)
Recommended Standards
- Vildagliptin Impurity 19 (CAS 243145-00-8)
- Benzophenone Hydrazone (CAS 5350-57-2)
- Clavulanate Potassium EP Impurity C (CAS 86917-74-0)
- 3530-82-3 5-Benzylhydantoin 5-(Phenylmethyl)imidazolidine-2,4-dione EINECS 222-563-3 NSC 30459 NSC 50842 (CAS 3530-82-3)
- Baricitinib Impurity 113 (CAS 1911644-33-1)
- Nilotinib Hydrochloride Monohydrate EP Impurity C (CAS 2458-12-0)
- Pregabalin Impurity PD224378 (CAS 501665-88-9)
- N-(4-Chlorophenyl)-2-nitro-N-{[3-oxo-2-benzofuran-1(3H)-yliden]methyl}ethanimidohydrazide (CAS 1164476-34-9)
- 3-(5-Chloro-2-fluorophenyl)-1-methyl-1h-pyrazol-5-amine (CAS 1152666-84-6)
- Lead(IV)oxide (CAS 1309-60-0)
- 3-Amino-4-(4-bromophenoxy)-n,n-diethylbenzene-1-sulfonamide (CAS 735322-73-3)
- 3-(4,5-dihydro-1H-imidazol-2-ylsulfanyl)-1H-indole (CAS 62882-99-9)
- 3-(4-Chlorobutanamido)benzofuran-2-carboxamide (CAS 898372-92-4)
- Acetyl Hexapeptide-39 (CAS 1382088-38-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com