Amorolfine Impurity 86 CAS 27110-75-4
| CAS No. | 27110-75-4 |
| Molecular Formula | C10H12ClNO |
| Molecular Weight | 197.66 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Amorolfine Impurity 86 (C10H12ClNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Amorolfine Impurity 86 (CAS 27110-75-4), a pharmacopoeial impurity reference standard (molecular formula C10H12ClNO, MW 197.66 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Amorolfine Impurity 86 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H12ClNO |
| Molecular Weight | 197.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Amorolfine Standards
- Amorolfine EP Impurity F (CAS 106614-66-8)
- Amorolfine lmpurity 66 (CAS CATO-C4X-154266)
- Amorolfine Impurity 50 (CAS 67468-55-7)
- Amorolfine Impurity N1 (CAS 67467-96-3)
- Amorolfine Impurity 31 (CAS CATO-C4X-154231)
- Amorolfine Impurity 32 (CAS CATO-C4X-154232)
- Amorolfine Impurity 55 (CAS CATO-C4X-154255)
- Amorolfine Impurity 65 (CAS CATO-C4X-154265)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com