Sitagliptin Impurity 163 CAS 2945884-76-2
| CAS No. | 2945884-76-2 |
| Molecular Formula | C7H7F3O2 |
| Molecular Weight | 180.12 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Sitagliptin Impurity 163 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Sitagliptin Impurity 163 (CAS 2945884-76-2), a pharmacopoeial impurity reference standard (molecular formula C7H7F3O2, MW 180.12 g/mol) used for the identification and quantification of trace impurities in APIs.
Sitagliptin Impurity 163 (C7H7F3O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C7H7F3O2 |
| Molecular Weight | 180.12 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2004 |
| Halogen Content | F-containing |
Related Sitagliptin Standards
- Sitagliptin Impurity 107 (CAS 89124-06-1)
- Sitagliptin Impurity 62 (CAS 723286-98-4)
- Sitagliptin Impurity 80 (CAS 220199-85-9)
- Sitagliptin Impurity 67 (CAS CATO-C4X-114467)
- Sitagliptin Impurity 80 (CAS 658-93-5)
- Sitagliptin Impurity 79 (CAS 81228-09-3)
- Sitagliptin Impurity 78 (CAS 85068-27-5)
- Sitagliptin Impurity 60 (CAS 1305324-02-0)
Recommended Standards
- Pteridine-2,4,7(1H,3H,8H)-trione (CAS 2577-38-0)
- Valaciclovir Nitroso Impurity 48 (CAS CATO-C4X-124848)
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- 2-[3-(trifluoromethyl)-1h-pyrazol-1-yl]ethan-1-ol (CAS 1006344-06-4)
- Sofosbuvir Impurity 43 (CAS CATO-C4X-105243)
- Cefalotin Impurity 9 (CAS CATO-C4X-12849)
- Resmetirom Impurity 51 (CAS CATO-C4X-291251)
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- 2,4-Difluorobenzylamine (CAS 72235-52-0)
- Mast Cell Degranulating (MCD) Peptide HR-2 (CAS 80388-04-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com