Fosaprepitant Impurity 25 Dimeglumine CAS 2975348-16-2
| CAS No. | 2975348-16-2 |
| Molecular Formula | C23H23F6N4O6P |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Fosaprepitant Impurity 25 Dimeglumine (CAS 2975348-16-2), a pharmacopoeial impurity reference standard (molecular formula C23H23F6N4O6PC7H17NO5, MW 791.64 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Fosaprepitant Impurity 25 Dimeglumine (C23H23F6N4O6PC7H17NO5) contains a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.5, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 791.64 g/mol, it falls into the high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C23H23F6N4O6P 2*C7H17NO5 |
| Molecular Weight | 791.64 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2004 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Fosaprepitant Standards
- Fosaprepitant impurity 55（R,S,R） (CAS 1185503-00-7(free base))
- Fosaprepitant Impurity 53 (CAS 1254261-32-9)
- Fosaprepitant Impurity 4 Dimeglumine (CAS 1523569-87-0)
- Fosaprepitant Impurity 19 (CAS 1623-07-0)
- Fosaprepitant Impurity 48 (CAS 1707-92-2)
- Fosaprepitant Impurity 6 (CAS 172822-01-4（free base）)
- Fosaprepitant Impurity 12 (CAS 2035475-10-4)
- Fosaprepitant Impurity 41 HCl (CAS 2377328-02-2)
Recommended Standards
- Sarpogrelate Impurity 4 (CAS CATO-C4X-29134)
- Carbidopa EP Impurity H HCl (CAS CATO-C4X-231015)
- Tapentadol EP Impurity D (CAS CATO-C4X-209920)
- 2-Naphthalenecarboxamide, 4-[2-[4-(aminocarbonyl)phenyl]diazenyl]-3-hydroxy-N-(2-methoxyphenyl)- (CAS 36968-27-1)
- N-((1-Ethyl-3-methyl-1H-pyrazol-4-yl)methyl)-1-(2-fluoroethyl)-4-methyl-1H-pyrazol-3-amine hydrochloride (CAS 1856019-72-1)
- [1,1'-Biphenyl]-4-yl carbonochloridate (CAS 3185-73-7)
- tert-Butyl 2-(3-aminoazetidin-1-yl)acetate (CAS 1493642-45-7)
- 3-(2-bromophenyl)-2-[(dimethylamino)methyl]-3-hydroxypropanenitrile (CAS 1049606-74-7)
- 5-Bromo-2-fluorobenzoic Acid (CAS 146328-85-0)
- Anti-Inflammatory Peptide 1 (CAS 118850-71-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com