Betamethasone impurity 71 CAS 37926-76-4
| CAS No. | 37926-76-4 |
| Molecular Formula | C22H29FO5 |
| Molecular Weight | 392.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C22H29FO5, Betamethasone impurity 71 contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 392.46 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Betamethasone impurity 71 (CAS 37926-76-4) is a certified pharmaceutical impurity reference standard with the molecular formula C22H29FO5 and a molecular weight of 392.46 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Betamethasone impurity 71 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H29FO5 |
| Molecular Weight | 392.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | F-containing |
Related Betamethasone Standards
- Betamethasone Impurity 22 (CAS 2990-65-0)
- Betamethasone EP Impurity H (CAS 185613-71-2)
- Betamethasone Impurity 117 (CAS CATO-C4X-1437117)
- Betamethasone Impurity 145 (CAS CATO-C4X-1437145)
- Betamethasone Impurity 34(Mixture of Diastereomers) (CAS 1249-19-0)
- Betamethasone EP Impurity I (CAS 185613-69-8)
- Betamethasone impurity 97 (CAS 1150311-95-7)
- Betamethasone impurity 98 (CAS CATO-C4X-143798)
Recommended Standards
- Fluticasone Impurity 56 (CAS CATO-C4X-165056)
- Dexamethasone impurity 69 (CAS CATO-C4X-116569)
- Fluorometholone Impurity 8 (CAS CATO-C4X-19338)
- Dexamethasone impurity 68 (CAS CATO-C4X-116568)
- Fosfomycin Impurity 72 (CAS 26017-01-6)
- Edoxaban Impurity 10 (CAS CATO-C4X-106310)
- Ramosetron Impurity 15 (CAS 26751-24-6)
- 3-(Benzyloxy)-1-(hydroxymethyl)cyclobutanecarbonitrile (CAS 1181816-14-7)
- Methyl 3-(((benzyloxy)carbonyl)(methyl)amino)propanoate (CAS 109141-51-7)
- Ethyl 5-amino-1,2,4-thiadiazole-3-carboxylate (CAS 150056-39-6)
- 1-Bromo-4-butylthiobenzene (CAS 121392-35-6)
- 2-Ethoxy-3,5-dimethylbenzaldehyde (CAS 883536-29-6)
- n-((4-Chlorophenyl)sulfonyl)-n-(3,4-dimethylphenyl)glycine (CAS 769930-41-8)
- Tirzepatide Impurity 34 (CAS CATO-C4X-324034)
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