Trimethoprim EP Impurity I(Mixture of cis/trans isomers) CAS 30078-48-9
| CAS No. | 30078-48-9 |
| Molecular Formula | C19H20N2O3 |
| Molecular Weight | 324.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Trimethoprim EP Impurity I(Mixture of cis/trans isomers) (CAS 30078-48-9) is a certified pharmaceutical impurity reference standard with the molecular formula C19H20N2O3 and a molecular weight of 324.37 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Trimethoprim EP Impurity I(Mixture of cis/trans isomers) is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 324.37 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Trimethoprim EP Impurity I(Mixture of cis/trans isomers) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H20N2O3 |
| Molecular Weight | 324.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Nitrogen Atoms | 2 |
Related Trimethoprim Standards
- Trimethoprim EP Impurity I (CAS CATO-C4X-122519)
- Trimethoprim EP Impurity I (E-Isomer) (CAS 118791-61-0)
- Trimethoprim EP Impurity F (CAS 16285-82-8)
- Trimethoprim N-Oxide 1 (CAS 27653-68-5)
- Trimethoprim N-Oxide 3 (CAS 27653-67-4)
- Trimethoprim EP Impurity C (CAS 29606-06-2)
- Trimethoprim EP Impurity A (CAS 213745-86-9)
- Trimethoprim Impurity 12 (CAS 92653-78-6)
Recommended Standards
- Tiopronin Impurity 1 (CAS 21269-37-4)
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- Phloroglucinol impurity 45 (CAS 634-94-6)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com