Remimazolam Impurity 4 CAS 308242-23-1
| CAS No. | 308242-23-1 |
| Molecular Formula | C18H16BrN3O3 |
| Molecular Weight | 402.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Remimazolam Impurity 4 (CAS 308242-23-1, C18H16BrN3O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution, Remimazolam Impurity 4 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 402.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Remimazolam Impurity 4 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H16BrN3O3 |
| Molecular Weight | 402.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Remimazolam Standards
- Remimazolam Impurity 1 (CAS 1275616-59-5)
- Remimazolam Impurity 6 (CAS 1449295-47-9)
- Remimazolam Impurity 1 (CAS CATO-C4X-28231)
- Remimazolam Impurity 7 (CAS CATO-C4X-28237)
- Remimazolam Impurity 5 (CAS 1276185-51-3)
- Remimazolam Impurity 2 (CAS 960305-91-3)
- Remimazolam Impurity 17 (CAS CATO-C4X-282317)
- Remimazolam Impurity 12 (CAS 308243-65-4)
Recommended Standards
- tert-Butyl 4-(2-amino-5-bromo-3-nitropyridin-4-yl)piperazine-1-carboxylate (CAS 942948-13-2)
- Methyl 2-bromo-5-fluoro-3-((4-methylphenyl)sulfonamido)benzoate (CAS 2086689-91-8)
- 2-[2-(5-Iodo-thiophen-2-yl)-ethyl]-6-methoxy-benzoic acid methyl ester (CAS 1171924-34-7)
- Benzyl 2-bromo-4-(1,3-dioxoisoindolin-2-yl)butanoate (CAS 39257-86-8)
- Fluvastatin Impurity 17 (CAS CATO-C4X-165117)
- Cenobamate Impurity 25 (CAS CATO-C4X-241625)
- Cyclosporin Impurity 13 (CAS CATO-C4X-199813)
- 3-(Difluoromethyl)-5-methyl-4,5-dihydro-1H-pyrazol-5-ol (CAS 933768-35-5)
- Taletrectinib Impurity1 (CAS 928333-30-6)
- 9-Cyclopropyl-9-azabicyclo[3.3.1]nonane-3-carboxylic acid (CAS 1209589-45-6)
- 3-Fluoro-2-(N-morpholino)phenol (CAS 1171917-65-9)
- 2-(4-Cyanobenzenesulfonamido)propanoic acid (CAS 1308963-00-9)
- 3-((3,5-Dichlorophenyl)amino)-3-oxopropanoic acid (CAS 53219-94-6)
- Tirzepatide Impurity 34 (CAS CATO-C4X-324034)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com