Rivaroxaban Impurity 22 CAS 31166-29-7

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.31166-29-7
Molecular FormulaC5H2Cl2O2S
Molecular Weight197.04 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Rivaroxaban Impurity 22 CAS 31166-29-7 chemical structure

Description

The occurrence of Rivaroxaban Impurity 22 is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Rivaroxaban Impurity 22 (CAS 31166-29-7) is a certified pharmaceutical impurity reference standard with the molecular formula C5H2Cl2O2S and a molecular weight of 197.04 g/mol.

The molecular framework of Rivaroxaban Impurity 22 (C5H2Cl2O2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Rivaroxaban Impurity 22 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC5H2Cl2O2S
Molecular Weight197.04 g/mol
Purity97%+
StorageStore at 2-8°C, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1965
Halogen ContentCl-containing
Sulfur Atoms1

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