Avanafil Impurity 130 CAS CATO-C4X-1118130
| CAS No. | CATO-C4X-1118130 |
| Molecular Formula | C20H24ClN5O5 |
| Molecular Weight | 449.89 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Avanafil Impurity 130 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Avanafil Impurity 130 (CAS CATO-C4X-1118130, C20H24ClN5O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Avanafil Impurity 130 (C20H24ClN5O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 449.89 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C20H24ClN5O5 |
| Molecular Weight | 449.89 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Avanafil Standards
- Avanafil Impurity 148 (CAS CATO-C4X-1118148)
- Avanafil Impurity 6 (CAS 330784-50-4)
- Avanafil Impurity 104 (CAS CATO-C4X-1118104)
- Avanafil Impurity 3 (CAS 1364671-52-2)
- Avanafil Impurity 155 (CAS CATO-C4X-1118155)
- Avanafil Impurity 63 (CAS CATO-C4X-111863)
- Avanafil Impurity 21 (CAS CATO-C4X-111821)
- Avanafil Impurity 139 (CAS CATO-C4X-1118139)
Recommended Standards
- tert-Butyl 4-(5-((6-chloro-4-(methoxycarbonyl)pyridin-2-yl)oxy)pyrimidin-2-yl)piperazine-1-carboxylate (CAS 2007908-94-1)
- 2-(2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)acetamido)-N,3,3-trimethylbutanamide (CAS 318949-39-2)
- Ethyl 3-({N'-[(1E)-(4-chlorophenyl)methylidene]hydrazinecarbonyl}methoxy)pyrido[1,2-a]indole-10-carboxylate (CAS 339020-49-4)
- 5-Chloro-2-methoxy-N-{1-[3-(pyrazin-2-yl)-1,2,4-oxadiazol-5-yl]cyclohexyl}benzene-1-sulfonamide (CAS 1396865-20-5)
- Vericiguat Impurity 10 (CAS CATO-C4X-289610)
- Thioctic Acid Impurity 24 (CAS CATO-C4X-152653)
- Selegiline Impurity 11 (CAS CATO-C4X-191611)
- 5-(Tert-butyl) 3-ethyl 4-methyl-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-3,5-dicarboxylate (CAS 2306262-60-0)
- 3-Chloro-1-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one (CAS 1823183-80-7)
- 6-Fluoro-3-methyl-3-propyl-3,4-dihydro-2H-[1,3'-biquinolin]-2-one (CAS 918645-98-4)
- 1,3,6-Tribromopyrene (CAS 38303-36-5)
- 6-Chloro-2-(3-hydroxyphenyl)quinoline-4-carboxylic acid (CAS 724749-33-1)
- 3-(Methoxymethyl)-5-methyl-1H-pyrazole-4-carboxylic acid (CAS 1239473-55-2)
- D-[Asp]9-Semaglutide (CAS CATO-CPTD788631)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com