Loperamide Hydrochloride CAS 34552-83-5
| CAS No. | 34552-83-5 |
| Molecular Formula | C29H33ClN2O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Loperamide Hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Loperamide Hydrochloride (CAS 34552-83-5) is a high-purity analytical reference standard with the molecular formula C29H33ClN2O2HCl and a molecular weight of 513.50 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Loperamide Hydrochloride is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 513.50 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C29H33ClN2O2 HCl |
| Molecular Weight | 513.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Loperamide Standards
- Loperamide EP Impurity F (CAS 106900-12-3)
- Loperamide EP Impurity G (CAS 109572-89-6)
- Loperamide EP Impurity G HCl (CAS 109572-89-6(free base))
- Loperamide EP Impurity D HCl (CAS 1134369-22-4)
- Loperamide impurity 14 (CAS 113817-55-3)
- Loperamide EP Impurity A (CAS 1391052-94-0)
- Loperamide EP Impurity E (CAS 1426322-82-8)
- Loperamide N-Oxide (CAS 217471-03-9)
Recommended Standards
- 4-Nitrobenzyl[2r-(2alpha,5beta,6alpha,7beta)]-3-methylene-8-oxo-7-(phenoxyacetamido)-5-thia-1-azabicyclo[4.2.0]octane-2-carboxylate5-oxide (CAS 60771-27-9)
- 3-(Tert-butoxycarbonyl)-1a,2,3,7b-tetrahydro-1H-cyclopropa[c][1,8]naphthyridine-6-carboxylic acid (CAS 2278294-68-9)
- 4-Cyclopropyl-1H-imidazole-2-carbonitrile hydrochloride (CAS 2173991-69-8)
- Etoricoxib Impurity 75 (CAS 40061-49-2)
- H-Glu-Arg-OH acetate salt (CAS 7219-59-2)
- Ampicillin Impurity 99 (CAS CATO-C4X-144399)
- Diphenyl (4-methyl-1,3-phenylene)dicarbamate (CAS 4223-24-9)
- 5-Fluoro-2-methoxyisonicotinonitrile (CAS 1256804-96-2)
- 5-(1,3-Benzodioxol-5-yl)isoxazole-3-carbohydrazide (CAS 1142210-96-5)
- [D-His1]-Semaglutide (CAS CATO-C4X-2226127)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com