Loperamide N-Oxide CAS 217471-03-9
| CAS No. | 217471-03-9 |
| Molecular Formula | C29H33ClN2O3 |
| Molecular Weight | 493.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Loperamide N-Oxide is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Loperamide N-Oxide (CAS 217471-03-9) is a high-purity analytical reference standard with the molecular formula C29H33ClN2O3 and a molecular weight of 493.04 g/mol.
Based on its molecular formula C29H33ClN2O3, Loperamide N-Oxide contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 493.04 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Loperamide N-Oxide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C29H33ClN2O3 |
| Molecular Weight | 493.04 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2019 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Loperamide Standards
- Loperamide EP Impurity G (CAS 109572-89-6)
- Loperamide EP Impurity G (CAS CATO-C4X-178810)
- Loperamide EP Impurity F (CAS 106900-12-3)
- Loperamide impurity 12 (CAS CATO-C4X-178812)
- Loperamide (CAS 53179-11-6)
- Loperamide EP Impurity H (CAS 61299-42-1)
- Loperamide Impurity 16 (CAS CATO-C4X-178816)
- Loperamide EP Impurity D (CAS 37743-41-2)
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- 6-(4-Chlorophenyl)-5-methylpyrimidin-4-ol (CAS 1256778-65-0)
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- 2-Cyclopropylpyrimidine-5-carboxylic Acid (CAS 648423-79-4)
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- Semaglutide Impurity 12 (CAS CATO-C4X-222612)
Why CATO?
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