Roflumilast Impurity 30 CAS 34809-82-0
| CAS No. | 34809-82-0 |
| Molecular Formula | C8H6O3 |
| Molecular Weight | 150.13 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Roflumilast Impurity 30.
CATO supplies Roflumilast Impurity 30 (CAS 34809-82-0), a pharmacopoeial impurity reference standard (molecular formula C8H6O3, MW 150.13 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, Roflumilast Impurity 30 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 150.13 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H6O3 |
| Molecular Weight | 150.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | ＞95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
Related Roflumilast Standards
- Roflumilast impurity 22 (CAS 343927-62-8)
- Roflumilast USP Related Compound C (CAS 22889-78-7)
- Roflumilast impurity 18 (CAS 7051-34-5)
- Roflumilast Impurity 31 (CAS 268225-79-2)
- Roflumilast Impurity 27 (CAS 74976-40-2)
- Roflumilast Impurity 17 (CAS 91872-02-5)
- Roflumilast Impurity 13 (CAS 53173-70-9)
- Roflumilast impurity 19 (CAS 151103-08-1)
Recommended Standards
- 2,3-(Methylenedioxy)benzaldehyde (CAS 7797-83-3)
- 【禁售不询】Tadalafil Impurity 43 (CAS 120-57-0)
- D-Xylulose(0.5 M in Water) (CAS 551-84-8)
- Olaparib Impurity 31 (CAS 16859-59-9)
- Dorzolamide EP Impurity D (CAS 154154-90-2)
- Etoricoxib impurity 54 (CAS 646459-47-4)
- Ivabradine impurity 84 (CAS 869856-10-0)
- Ethyl 2-iodo-3,4-dimethoxybenzoate (CAS 210538-61-7)
- 4-Chloro-2-fluoropyridine (CAS 169452-07-7)
- 3-(Difluoromethyl)-5-fluoropyridine (CAS 1374659-37-6)
- 3,4-Dihydro-1H-benzo[c]azepine-1,5(2H)-dione (CAS 41764-17-4)
- Orforglipron impurity 32 (CAS CATO-C4X-323432)
- 4-(Difluoromethoxy)-3,5-dimethylaniline (CAS 87310-15-4)
- Dendroaspis Natriuretic Peptide (CAS 255721-52-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com