Fluocortolone Impurity 6 CAS 36130-02-6

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.36130-02-6
Molecular FormulaC27H37FO5
Molecular Weight460.58 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Fluocortolone Impurity 6 CAS 36130-02-6 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 460.58 g/mol gives Fluocortolone Impurity 6 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Fluocortolone Impurity 6 (CAS 36130-02-6) is a certified pharmaceutical impurity reference standard with the molecular formula C27H37FO5 and a molecular weight of 460.58 g/mol.

Owing to a steroid core, a hydroxyl group, an ether linkage, fluorine substitution, Fluocortolone Impurity 6 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 460.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Fluocortolone Impurity 6 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC27H37FO5
Molecular Weight460.58 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1967
Halogen ContentF-containing

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