Fluocortolone Pivalate CAS 29205-06-9
| CAS No. | 29205-06-9 |
| Molecular Formula | C27H37FO5 |
| Molecular Weight | 460.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Fluocortolone Pivalate (CAS 29205-06-9), molecular formula C27H37FO5 and molecular weight 460.58 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Fluocortolone Pivalate (C27H37FO5) is characterized by a steroid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C27H37FO5 |
| Molecular Weight | 460.58 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | F-containing |
Related Fluocortolone Standards
- Fluocortolone Impurity 6 (CAS 36130-02-6)
- Fluocortolone Impurity 9 (CAS CATO-C4X-22309)
- Fluocortolone Pivalate EP Impurity D (CAS CATO-C4X-223014)
- Fluocortolone Impurity 8 (CAS CATO-C4X-22308)
- Fluocortolone Hexanoate (CAS 303-40-2)
- Fluocortolone Impurity 10 (CAS CATO-C4X-223010)
- Fluocortolone Impurity 11 (CAS CATO-C4X-223011)
- Fluocortolone Impurity 12 (CAS 66233-46-3)
Recommended Standards
- 10-(Triphenylphosphoranylidene)decyl acetate (CAS 88634-88-2)
- N,N-Dibenzyl-N'-[(benzylcarbamothioyl)amino]butanediamide (CAS 331461-08-6)
- Ethyl 2-(4-(3-(4-(tosyloxy)butoxy)propoxy)butoxy)acetate (CAS 2681388-10-1)
- Vortioxetine Impurity 28 (CAS 2135577-60-3)
- N-[trans-4-[tert-butyl(dimethyl)silyl]oxycyclohexyl]-2-chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-4-amine (CAS 2304631-70-5)
- 1-(pyridin-3-yl)methylpiperidine-3-carboxylic acid dihydrochloride 887445-00-3 (CAS 887445-00-3)
- cis-3-Hexenal-d (CAS 164668-82-0)
- N-(2-(1H-Pyrazol-1-yl)-1H-indol-4-yl)-3-methylbutanamide (CAS 827318-40-1)
- Opicapone impurity 71 (CAS CATO-C4X-240471)
- 1-(6-Chloropyridin-2-yl)-3-(methylthio)-1H-1,2,4-triazol-5-amine (CAS 338786-65-5)
- (Tert-butoxycarbonyl)leucine (CAS 64727-35-1)
- 6-Iodo-5-methoxypyridin-3-ol (CAS 1299607-66-1)
- 2-Amino-5-(sec-butyl)-4-oxo-4,5-dihydro-1h-pyrrole-3-carboxamide (CAS 929974-64-1)
- Liraglutide(8-31)TFA Salt (CAS CATO-C4X-19922)
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