Gefitinib Impurity 22 CAS 52805-46-6

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.52805-46-6
Molecular FormulaC8H7NO2
Molecular Weight149.15 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Gefitinib Impurity 22 CAS 52805-46-6 chemical structure

Description

Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Gefitinib Impurity 22 is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 149.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Gefitinib Impurity 22 (CAS 52805-46-6) is a certified pharmaceutical impurity reference standard with the molecular formula C8H7NO2 and a molecular weight of 149.15 g/mol.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Gefitinib Impurity 22 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H7NO2
Molecular Weight149.15 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1972
Nitrogen Atoms1

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