Alprazolam EP Impurity C CAS 36916-19-5
| CAS No. | 36916-19-5 |
| Molecular Formula | C16H12ClN3O |
| Molecular Weight | 297.74 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Alprazolam EP Impurity C (CAS 36916-19-5), a pharmacopoeial impurity reference standard (molecular formula C16H12ClN3O, MW 297.74 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Alprazolam EP Impurity C is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 297.74 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures Alprazolam EP Impurity C under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H12ClN3O |
| Molecular Weight | 297.74 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Alprazolam Standards
- Alprazolam EP Impurity A (CAS 27537-87-7)
- Alprazolam Impurity 2 (CAS 4016-85-7)
- Alprazolam impurity 24 (CAS CATO-C4X-146024)
- Alprazolam impurity 25 (CAS CATO-C4X-146025)
- Alprazolam Impurity 26 (CAS CATO-C4X-146026)
- Alprazolam impurity 27 (CAS CATO-C4X-146027)
- Alprazolam EP Impurity G (CAS 448950-89-8)
- Alprazolam (CAS 28981-97-7)
Recommended Standards
- 92434-13-4 N-(6-Chloro-4-phenylquinazolin-2-yl)guanidine MFCD02816999 (CAS 92434-13-4)
- Famciclovir Impurity 13 (CAS CATO-C4X-164213)
- 4-[(Z)-2-(4-chlorophenyl)ethenyl]-2-[(1H-1,2,4-triazol-1-yl)methyl]pyrimidine 400083-23-0 5F-038 (CAS 400083-23-0)
- Hydrochlorothiazide (CAS 58-93-5)
- S-Adenosyl-L-Methionine Impurity 26 4-sulfobutane-1-sulfonate (CAS CATO-C4X-138126)
- Dotinurad Impurity 91 (CAS CATO-C4X-249491)
- Rosuvastatin Impurity 212 (CAS CATO-C4X-1169212)
- (1-((4-Fluorophenyl)sulfonyl)piperidine-3-carbonyl)glycine (CAS 929856-87-1)
- Fluorescamine (CAS 38183-12-9)
- 2,5-Dibromo-1-methyl-3-nitrobenzene (CAS 408340-39-6)
- 3-Chloro-5-(cyclopropylethynyl)picolinonitrile (CAS 1803106-78-6)
- 3-(Aminomethyl)-4-cyclopropoxybenzaldehyde (CAS 1243359-25-2)
- N,N-Dimethyl-5-phenyl-1,3,4-oxadiazole-2-carbothioamide (CAS 89515-43-5)
- Semaglutide impurity 229 (CAS CATO-C4X-2226229)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com