Alprazolam EP Impurity D CAS CATO-C4X-146010
| CAS No. | CATO-C4X-146010 |
| Molecular Formula | C18H13ClN4 |
| Molecular Weight | 320.78 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Alprazolam EP Impurity D.
Alprazolam EP Impurity D (CAS CATO-C4X-146010) is a certified pharmaceutical impurity reference standard with the molecular formula C18H13ClN4 and a molecular weight of 320.78 g/mol.
Structurally, Alprazolam EP Impurity D (C18H13ClN4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 320.78 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Alprazolam EP Impurity D under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H13ClN4 |
| Molecular Weight | 320.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Alprazolam Standards
- Alprazolam Impurity 8 (CAS 30896-65-2)
- Alprazolam EP Impurity B (CAS CATO-C4X-146014)
- Alprazolam Impurity 16 (CAS CATO-C4X-146016)
- Alprazolam-D5 (CAS 125229-61-0)
- Alprazolam-D5 (1.0 mg/mL in Methanol) (CAS 1286073-82-2)
- Alprazolam EP Impurity B (CAS 38150-27-5)
- Alprazolam impurity 21 (CAS 37945-06-5)
- Alprazolam EP Impurity G (CAS 448950-89-8)
Recommended Standards
- 9-Benzhydryl-6-chloro-9H-purine (CAS 608523-18-8)
- Clofazimine Impurity 4 (CAS CATO-C4X-20714)
- 4-(4-Chlorophenyl)-6-(methylamino)-2-phenylpyrimidine-5-carbonitrile (CAS 320418-58-4)
- 2-Chloro-n-[5-(dimethylsulfamoyl)-2-methoxyphenyl]propanamide (CAS 1155000-26-2)
- Iguratimod Impurity 37 (CAS 1340086-28-3)
- Etelcalcetide impurity 38 (CAS CATO-C4X-324738)
- Lovastatin EP Impurity D (Lovastatin Dimer) (CAS 149756-62-7)
- 3-(2-(Tert-Butoxycarbonyl)-1,2,3,4-Tetrahydroisoquinolin-6-Yl)Propanoic Acid (CAS 1158756-02-5)
- 5-Ethylbenzo[d]oxazol-2-amine (CAS 1030574-69-6)
- [(S)-3-(Benzyl-cyclopropyl-amino)-piperidin-1-yl]-acetic acid (CAS 1354001-24-3)
- 4-[3-(Trifluoromethyl)phenoxy]but-2-yn-1-amine hydrochloride (CAS 2097936-61-1)
- 4-Bromo-N1-methyl-5-propoxybenzene-1,2-diamine (CAS 1373232-86-0)
- (3-Chloro-4-(isopentyloxy)phenyl)methanol (CAS 1247694-85-4)
- Semaglutide impurity 274 (CAS CATO-C4X-2226274)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com