Avanafil Impurity 74 CAS 372118-67-7
| CAS No. | 372118-67-7 |
| Molecular Formula | C5H7N3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 145.59 g/mol gives Avanafil Impurity 74 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Avanafil Impurity 74 (CAS 372118-67-7) is a certified pharmaceutical impurity reference standard with the molecular formula C5H7N3HCl and a molecular weight of 145.59 g/mol.
Avanafil Impurity 74 (C5H7N3HCl) contains a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Avanafil Impurity 74 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H7N3 HCl |
| Molecular Weight | 145.59 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Avanafil Standards
- Avanafil Impurity 77 (CAS 1201936-61-9)
- Avanafil Impurity 160 (CAS 1202002-16-1)
- Avanafil Impurity 3 (CAS 1364671-52-2)
- Avanafil Impurity 2 (CAS 1364671-62-4)
- Avanafil Impurity 110 (CAS 1368440-33-8)
- Avanafil Impurity 4 (CAS 1452128-53-8)
- Avanafil Impurity 133 (CAS 1508194-63-5)
- Avanafil Impurity 46 (CAS 1624833-89-1)
Recommended Standards
- Upadacitinib Impurity 12 (CAS 2095311-51-4)
- Thiotepa Impurity 1 (CAS 90877-51-3)
- Alectinib Impurity 67 (CAS CATO-C4X-283667)
- 3-Amino-1-(2-fluorophenyl)piperidin-2-one (CAS 1343318-18-2)
- 3,5-Dichlorobenzo[d]isothiazole (CAS 19331-17-0)
- 2-tert-Butyl-3-hydroxy-3H-isoindol-1-one (CAS 86809-31-6)
- 3-Bromo-5-[4-(trifluoromethoxy)phenyl]-pyridine (CAS 1181214-52-7)
- 2-(2,6-Dibromophenyl)acetonitrile (CAS 67197-53-9)
- n-(2,6-Diethylphenyl)-n-(4-formyl-1,3-thiazol-2-yl)acetamide (CAS 872108-12-8)
- Tau Peptide (268-282) trifluoroacetate salt (CAS 330456-37-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com