Neostigmine Impurity 11 CAS 39218-17-2
| CAS No. | 39218-17-2 |
| Molecular Formula | C10H16NO |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Neostigmine Impurity 11 (CAS 39218-17-2), a pharmacopoeial impurity reference standard (molecular formula C10H16NOCH3O4S, MW 277.33 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, Neostigmine Impurity 11 is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 277.33 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C10H16NO CH3O4S |
| Molecular Weight | 277.33 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1968 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Neostigmine Standards
- Neostigmine Bromide (CAS 114-80-7)
- Neostigmine bromide Impurity 14 (CAS 14318-66-2)
- Neostigmine Impurity 24 (CAS 15799-79-8)
- Neostigmine EP Impurity C (CAS 16088-19-0)
- Neostigmine Methyl Sulfate - Impurity A (Bromide Salt) (CAS 1620-19-5)
- Neostigmine Impurity 50 (CAS 16460-28-9)
- Neostigmine Impurity 4 (CAS 19962-04-0)
- Neostigmine impurity 31 (CAS 22237-93-0（free base）)
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- 1-(2-Methylpropyl)-1H-pyrazole-3-carbonitrile (CAS 1823402-52-3)
- 3-Bromo-4-phenylpyrrolidine-2,5-dione (CAS 1701644-38-3)
- 4-Fluoro-N-(2-phenylquinazolin-4-yl)benzamide (CAS 866155-25-1)
- tert-Butyl 2-(4-bromopyridin-2-yl)acetate (CAS 1266119-33-8)
- 1188964-92-2 K-1342 TERT-BUTYL 4-[(METHYLCARBAMOYL)METHYL]PIPERAZINE-1-CARBOXYLATE (CAS 1188964-92-2)
- (Des-Thr?)-Glucagon trifluoroacetate salt (CAS 1802078-27-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com