Loperamide EP Impurity C CAS 39512-49-7
| CAS No. | 39512-49-7 |
| Molecular Formula | C11H14ClNO |
| Molecular Weight | 211.69 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Loperamide EP Impurity C meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Loperamide EP Impurity C (CAS 39512-49-7) is a certified pharmaceutical impurity reference standard with the molecular formula C11H14ClNO and a molecular weight of 211.69 g/mol.
Based on its molecular formula C11H14ClNO, Loperamide EP Impurity C contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 211.69 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C11H14ClNO |
| Molecular Weight | 211.69 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Loperamide Standards
- Loperamide impurity 13 (CAS 37742-98-6)
- Loperamide impurity 14 (CAS 113817-55-3)
- Loperamide impurity 15 (CAS 37743-18-3)
- Loperamide EP Impurity B Chloride (CAS CATO-C4X-17882)
- Loperamide EP Impurity D HCl (CAS 1134369-22-4)
- Loperamide EP Impurity G HCl (CAS 109572-89-6(free base))
- Loperamide Impurity 8 HCl (CAS CATO-C4X-17888)
- Loperamide EP Impurity H HCl salt (CAS 61299-42-1(Free Base))
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