Olaparib Impurity 81 CAS 4122-57-0
| CAS No. | 4122-57-0 |
| Molecular Formula | C9H8O3 |
| Molecular Weight | 164.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Olaparib Impurity 81 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Olaparib Impurity 81 (CAS 4122-57-0), a pharmacopoeial impurity reference standard (molecular formula C9H8O3, MW 164.16 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Olaparib Impurity 81 (C9H8O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 164.16 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C9H8O3 |
| Molecular Weight | 164.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Related Olaparib Standards
- Olaparib Impurity 60 (CAS CATO-C4X-113560)
- Olaparib Impurity 80 (CAS 4122-56-9)
- Olaparib Impurity 73 (CAS 164149-28-4)
- Olaparib impurity 144 (CAS CATO-C4X-1135144)
- Olaparib Impurity 77 (CAS 1937362-45-2)
- Olaparib Impurity 33 (CAS 550363-85-4)
- Olaparib Impurity 104 (CAS 545348-09-2)
- Olaparib Impurity 64 (CAS 155295-47-9)
Recommended Standards
- Isavuconazole Impurity 206 (CAS CATO-C4X-1236206)
- Isavuconazole Impurity 3 (CAS 2734004-61-4)
- Esomeprazole Impurity 32 (CAS 2080-75-3)
- Fosfomycin Impurity 53 (CAS CATO-C4X-131653)
- Risperidone Impurity 32 (CAS 108855-18-1)
- Efinaconazole Impurity 13 (CAS CATO-C4X-124313)
- Iguratimod Impurity 62 (CAS CATO-C4X-182662)
- Methyl 5-amino-1H-indazole-1-carboxylate (CAS 500881-32-3)
- 2-((4-(4-Fluorophenyl)phthalazin-1-yl)thio)acetic acid (CAS 554404-23-8)
- Ethyl 7-bromo-2,4-dichloro-1,5-naphthyridine-3-carboxylate (CAS 2758819-88-2)
- 1-(3,4-Dichlorophenyl)heptan-1-one (CAS 68120-68-3)
- 2-Chloro-4-(1-piperazinyl)-benzaldehyde (CAS 20011-18-1)
- 3-(4-bromo-6-fluoro-1-oxo-isoindolin-2-yl)piperidine-2,6-dione (CAS 2410219-18-8)
- Prolactin-Releasing Peptide (1-31) (rat) (CAS 215510-06-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com