Lenvatinib Impurity 30 CAS 417717-04-5
| CAS No. | 417717-04-5 |
| Molecular Formula | C20H17ClN4O4 |
| Molecular Weight | 412.83 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Lenvatinib Impurity 30 is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Lenvatinib Impurity 30 (CAS 417717-04-5) is a certified pharmaceutical impurity reference standard with the molecular formula C20H17ClN4O4 and a molecular weight of 412.83 g/mol.
Structurally, Lenvatinib Impurity 30 (C20H17ClN4O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 412.83 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Lenvatinib Impurity 30 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H17ClN4O4 |
| Molecular Weight | 412.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Lenvatinib Standards
- Lenvatinib Impurity 89 (CAS CATO-C4X-114089)
- Lenvatinib Impurity 92 (CAS 2143930-76-9)
- Lenvatinib Impurity 121 (CAS CATO-C4X-1140122)
- Lenvatinib Impurity 43 (CAS 1882873-21-3)
- Lenvatinib Impurity 180 (CAS CATO-C4X-1140180)
- Lenvatinib Impurity 172 (CAS CATO-C4X-1140172)
- Lenvatinib Impurity 4 (CAS 417719-45-0)
- Lenvatinib Impurity 113 (CAS CATO-C4X-1140113)
Recommended Standards
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- 2,4,6-tribromo-5-(trifluoromethyl)benzene-1,3-diamine (CAS 646989-62-0)
- 3-(2-Chloro-4-fluorobenzyl)-5-(6-methoxynaphthalen-2-yl)-5-methylimidazolidine-2,4-dione (CAS 956782-57-3)
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- 2-(4-(4-(1-hydroxyethyl)phenyl)-1H-1,2,3-triazol-1-yl)acetic acid (CAS 2035032-87-0)
- 4-Nitro-1H-indazol-7-amine (CAS 89795-92-6)
- 6-(4-Ethylpiperazin-1-yl)-5-methylnicotinaldehyde (CAS 1355220-08-4)
- Fmoc-2-amino-5-phenyl(2,3-Difluoro)-L-pentanoic acid (CAS 2349313-65-9)
- (1-(Tert-butyl)-5-(trifluoromethyl)-1H-pyrazol-4-yl)(morpholino)methanone (CAS 956368-93-7)
- N-(4-aminobutyl)hydroxylamine dihydrochloride (CAS 2564-52-5)
- Tirzepatide Impurity 9 (CAS CATO-C4X-32409)
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