Hydroxychloroquine Impurity 68 CAS 23443-05-2
| CAS No. | 23443-05-2 |
| Molecular Formula | C9H6ClNO |
| Molecular Weight | 179.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Hydroxychloroquine Impurity 68 (CAS 23443-05-2), a pharmacopoeial impurity reference standard (molecular formula C9H6ClNO, MW 179.60 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Hydroxychloroquine Impurity 68 (C9H6ClNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 179.60 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H6ClNO |
| Molecular Weight | 179.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Hydroxychloroquine Standards
- Hydroxychloroquine Impurity 10 (CAS 86-99-7)
- Hydroxychloroquine Impurity 54 (CAS 880-09-1)
- Hydroxychloroquine Impurity 23 (CAS 69559-11-1)
- Hydroxychloroquine impurity 80 (CAS CATO-C4X-183580)
- Hydroxychloroquine Impurity 33 (CAS 74509-79-8)
- Hydroxychloroquine Impurity 11 (CAS 21617-12-9)
- Hydroxychloroquine EP Impurity G (CAS 86-98-6)
- Hydroxychloroquine Impurity 18 (CAS 140-80-7)
Recommended Standards
- 5-Chloro-8-hydroxyquinoline (CAS 130-16-5)
- Ketoprofen Impurity 112 (CAS 42872-32-2)
- 7-Chloro-8-quinolinol (CAS 876-86-8)
- Famotidine impurity 74 (CAS 90224-97-8)
- Carbazochrome Impurity 10 (CAS CATO-C4X-229110)
- Carbidopa EP Impurity G (CAS 2503-44-8)
- Minodronic Impurity 2 (CAS 19741-30-1)
- 3,5-Bis-benzyloxy-4-bromobenzoic acid tert-butyl ester (CAS 158980-57-5)
- (R)-O-Desmethyl-Venlafaxine-D6 (CAS 1062609-96-4)
- [1-(3-nitropyridin-2-yl)piperidin-4-yl]methanol (CAS 1235440-20-6)
- Epinastine Impurity 49 (CAS 2831006-70-1)
- (S)-3-(2-fluorophenyl)pyrrolidine (CAS 1336075-09-2)
- Dyclonine Impurity 13 (CAS 42528-76-7)
- Tau Peptide (74-102) (Exon 3/Insert 2 Domain) trifluoroacetate salt (CAS 1322695-34-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com