Propafenone Impurity 28 CAS CATO-C4X-132228
| CAS No. | CATO-C4X-132228 |
| Molecular Formula | C15H14O2 |
| Molecular Weight | 226.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Propafenone Impurity 28 (CAS CATO-C4X-132228) is a certified pharmaceutical impurity reference standard with the molecular formula C15H14O2 and a molecular weight of 226.27 g/mol.
Structurally, Propafenone Impurity 28 (C15H14O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 226.27 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H14O2 |
| Molecular Weight | 226.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Propafenone Standards
- Propafenone EP Impurity A (CAS 3516-95-8)
- Propafenone Impurity 29 (CAS 36941-00-1)
- Propafenone Impurity 31 (CAS CATO-C4X-132231)
- Propafenone Impurity 30 (CAS 17002-31-2)
- Propafenone EP Impurity H(R-isomer) (CAS 27439-12-9)
- Propafenone EP Impurity H (CAS 487-26-3)
- Propafenone RC 6 (CAS 189766-45-8)
- Propafenone Impurity 23 (CAS CATO-C4X-132223)
Recommended Standards
- Terbutaline Impurity 51 (CAS 34068-01-4)
- Temozolomide Impurity 26 (CAS 13114-72-2)
- Ibuprofen Impurity 26 (CAS 67173-18-6)
- Telmisartan Impurity 33 (CAS 114772-34-8)
- Tebipenem Impurity 16 (stabilized with Copper chip) (CAS 53064-79-2)
- Gefitinib Impurity 42 (CAS CATO-C4X-111742)
- Oxcarbazepine EP Impurity A (Carbamazepine) (CAS 298-46-4)
- Avibactam Impurity 1 (CAS 2243810-78-6)
- N-(4-Chlorophenyl)-2-((4,5-diphenyl-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 328020-51-5)
- 2-(2,3-Difluorophenyl)butanoic acid (CAS 1410428-44-2)
- 2-Bromoethanesulfonic Acid (CAS 26978-65-4)
- 3-Chloro-4-(4'-fluorobenzyloxy)phenylboronic acid (CAS 849062-39-1)
- 2-(Bromomethyl)-1-methyl-1H-imidazole hydrobromide (CAS 1864074-91-8)
- Semaglutide impurity 208 (CAS CATO-C4X-2226208)
Why CATO?
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