Minocycline EP Impurity A HCl CAS 43168-51-0(Free Base)
| CAS No. | 43168-51-0(Free Base) |
| Molecular Formula | C23H27N3O7 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Minocycline EP Impurity A HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Minocycline EP Impurity A HCl (CAS 43168-51-0(Free Base)), a pharmacopoeial impurity reference standard (molecular formula C23H27N3O7HCl, MW 493.94 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C23H27N3O7HCl, Minocycline EP Impurity A HCl contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 493.94 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C23H27N3O7 HCl |
| Molecular Weight | 493.94 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Minocycline Standards
- Minocycline Impurity N1 (CAS 10118-89-5)
- Minocycline (CAS 10118-90-8)
- Minocycline EP Impurity F (CAS 1075240-33-3)
- Minocycline Hydrochloride Dihydrate (CAS 128420-71-3)
- Minocycline EP Impurity H (CAS 1346598-44-4)
- Minocycline Hydrochloride (CAS 13614-98-7)
- Minocycline Impurity 26 (CAS 149934-16-7)
- Minocycline impurity 73 (CAS 156263-28-4)
Recommended Standards
- Bisoprolol Impurity 56 (CAS 145059-66-1)
- Venetoclax Impurity 119 (CAS CATO-C4X-2495119)
- Solriamfetol Impurity 5 (CAS CATO-C4X-25635)
- Phenyl(triethylgermyl)methanone (CAS 13433-78-8)
- 2,5-Dibromophenylboronic Acid (CAS 1008106-93-1)
- 3-fluoro-4-(methylamino)benzoic acid (CAS 1248597-55-8)
- 4-Cyclopropoxy-N1,N2-dimethylbenzene-1,2-diamine (CAS 1243376-69-3)
- 2-Isobutoxybenzoyl chloride (CAS 318729-75-8)
- (S)-2-Amino-3-(4-(prop-2-yn-1-yloxy)phenyl)propanoic acid (CAS 610794-20-2)
- Semaglutide Impurity 18 (CAS 1671100-14-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com