Nicorandil Impurity N1 CAS 46053-56-9
| CAS No. | 46053-56-9 |
| Molecular Formula | C8H10N2O2 |
| Molecular Weight | 166.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Nicorandil Impurity N1 (CAS 46053-56-9) is a certified pharmaceutical impurity reference standard with the molecular formula C8H10N2O2 and a molecular weight of 166.18 g/mol.
Nicorandil Impurity N1 (C8H10N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Nicorandil Impurity N1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H10N2O2 |
| Molecular Weight | 166.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1970 |
| Nitrogen Atoms | 2 |
Related Nicorandil Standards
- Nicorandil Impurity 17 (CAS 6265-74-3)
- Nicorandil EP Impurity B (CAS 6265-73-2)
- Nicorandil Impurity 47 (CAS 13362-26-0)
- Nicorandil Impurity 57 (CAS 342018-76-2)
- Nicorandil Impurity 26 (CAS 14906-63-9)
- Nicorandil Impurity 43 (CAS 1570-45-2)
- Nicorandil Impurity 13 (CAS 896133-95-2)
- Nicorandil Impurity 28 (CAS CATO-C4X-190728)
Recommended Standards
- N-Hydroxy-4-methoxy-benzamidine (CAS 5373-87-5)
- N-methoxy-N-methylnicotinamide (CAS 95091-91-1)
- N'-hydroxy-4-(hydroxymethyl)benzimidamide (CAS 635702-23-7)
- N-Methyl-2-nitrobenzylamine (CAS 56222-08-3)
- Cefazolin Impurity P5 (CAS CATO-C4X-157749)
- Betacarotene impurity 9 (CAS 3917-41-7)
- Riluzole Impurity 16 (CAS CATO-C4X-200916)
- Methyl 6-nitro-4-oxo-1,4-dihydroquinoline-2-carboxylate (CAS 16133-46-3)
- 8-bromo-1H-pyrazolo[1,5-a][1,3,5]triazine-2,4-dione (CAS 501681-75-0)
- 7-[(Anilinocarbonyl)amino]-5-methyl-3-phenyl-1H-indole-2-carboxylic acid (CAS 1171142-83-8)
- 4-Acetyl-2-amino-5-methylfuran-3-carbonitrile (CAS 108129-35-7)
- (5-Bromonaphthalen-1-yl)methanamine (CAS 681466-09-1)
- 2-Chloro-3-((3-(diethylamino)propyl)amino)naphthalene-1,4-dione (CAS 331462-38-5)
- 3AEEA-Semaglutide(Endo-AEEA-Semaglutide) (CAS CATO-C4X-2226265)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com