Empagliflozin Impurity 173 CAS 46698-24-2
| CAS No. | 46698-24-2 |
| Molecular Formula | C13H8BrFO |
| Molecular Weight | 279.10 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Empagliflozin Impurity 173 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Empagliflozin Impurity 173 (CAS 46698-24-2), a pharmacopoeial impurity reference standard (molecular formula C13H8BrFO, MW 279.10 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Empagliflozin Impurity 173 (C13H8BrFO) is characterized by a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C13H8BrFO |
| Molecular Weight | 279.10 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1970 |
| Halogen Content | F/Br-containing |
Related Empagliflozin Standards
- Empagliflozin Impurity 28 (CAS 19094-56-5)
- Empagliflozin Impurity 78 (CAS 874817-93-3)
- Empagliflozin Impurity 2 (CAS 2517968-35-1)
- Empagliflozin Impurity 174 (CAS 270903-87-2)
- Empagliflozin Impurity 33 (CAS CATO-C4X-106533)
- Empagliflozin Impurity 03 (CAS 312749-31-8)
- Empagliflozin Impurity 90 (CAS 620621-48-9)
- Empagliflozin impurity 56 (CAS 1628918-33-1)
Recommended Standards
- (E)-ethyl 2-chloro-2-(2-(3-chloro-4-fluorophenyl)hydrazono)acetate 81321-37-1 Ethyl 2-chloro-2-[2-(3-chloro-4-fluorophenyl)-hydrazono]acetate (CAS 81321-37-1)
- Cyclophosphamide Impurity 22 (CAS 3308-51-8)
- N-(5-Iodo-2-pyridinyl)thiourea (CAS 338748-96-2)
- Cyclophosphamide impurity 32 (CAS CATO-C4X-230632)
- Venetoclax Impurity 59 (CAS CATO-C4X-249559)
- Dronedarone Impurity 63 (CAS 90050-13-8)
- Dapagliflozin Impurity 49 (CAS 1408077-50-8)
- (S)-2-(o-tolyl)pyrrolidine (CAS 914299-82-4)
- (4-Bromo-1-methyl-1H-pyrazol-3-yl)methanamine hydrochloride (CAS 1956307-62-2)
- 4-Chloro-2-(2,2-dibromovinyl)-1-fluorobenzene (CAS 1881272-50-9)
- 2-Amino-5-oxo-4-(m-tolyl)-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (CAS 414896-26-7)
- Methyl 2,5-dichloro-6-(methylamino)pyrimidine-4-carboxylate (CAS 1423757-79-2)
- Choline fluoride (CAS 4696-35-9)
- D-γ-Glu20-Side-Tirzepatide (CAS CATO-CPTD788929)
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