Bisoprolol Impurity 68 CAS 325147-81-7
| CAS No. | 325147-81-7 |
| Molecular Formula | C9H12O3 |
| Molecular Weight | 168.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Bisoprolol Impurity 68 (CAS 325147-81-7) is a certified pharmaceutical impurity reference standard with the molecular formula C9H12O3 and a molecular weight of 168.19 g/mol.
Bisoprolol Impurity 68 (C9H12O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H12O3 |
| Molecular Weight | 168.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
Related Bisoprolol Standards
- Bisoprolol Impurity 95 (CAS CATO-C4X-124795)
- Bisoprolol Impurity 96 (CAS CATO-C4X-124796)
- Bisoprolol Impurity 74 (CAS 14435-48-4)
- Bisoprolol Impurity 36 (CAS 14697-49-5)
- Bisoprolol Impurity 37 (CAS 4204-78-8)
- Bisoprolol Impurity 104 (CAS CATO-C4X-1247104)
- Bisoprolol Impurity 69 (CAS 81349-58-8)
- Bisoprolol Impurity 49 (CAS 104857-48-9)
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