Tofacitinib Impurity 211 CAS CATO-C4X-1079211
| CAS No. | CATO-C4X-1079211 |
| Molecular Formula | C19H20Cl2N8 |
| Molecular Weight | 431.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Tofacitinib Impurity 211 (CAS CATO-C4X-1079211), a pharmacopoeial impurity reference standard (molecular formula C19H20Cl2N8, MW 431.32 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, Tofacitinib Impurity 211 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 431.32 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Tofacitinib Impurity 211 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H20Cl2N8 |
| Molecular Weight | 431.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 8 |
Related Tofacitinib Standards
- Tofacitinib Impurity 244 (CAS 2504210-48-2)
- Tofacitinib Impurity 109 (CAS CATO-C4X-1079109)
- Tofacitinib Impurity 105 (CAS 2459302-85-1)
- Tofacitinib Impurity 241 (CAS CATO-C4X-1079241)
- Tofacitinib Impurity 152 (CAS CATO-C4X-1079152)
- Tofacitinib Impurity 8 (CAS CATO-C4X-10798)
- Tofacitinib Impurity 163 (CAS CATO-C4X-1079163)
- Tofacitinib Impurity 210 (CAS CATO-C4X-1079210)
Recommended Standards
- 4-Chloro-5-(4-(3-chlorophenyl)piperazin-1-yl)-2-(4-methoxyphenyl)pyridazin-3(2H)-one (CAS 477867-46-2)
- Clofazimine Impurity 26 (CAS CATO-C4X-207126)
- 2-Bromo-6-(7,7-dimethyl-1-oxo-1,3,4,6,7,8-hexahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-2-yl)benzyl acetate (CAS 1346674-24-5)
- Clofazimine Impurity 28 (CAS CATO-C4X-207128)
- Relebactam Impurity 73 (CAS CATO-C4X-214473)
- Olaparib Impurity 6 (CAS 763113-06-0)
- Milrinone Impurity 23 (CAS 88349-61-5)
- 6,8-Dichloro-1h,2h,3h,4h,5h-pyrido[4,3-b]indole hydrochloride (CAS 1197477-27-2)
- 4-Acetylbenzenesulfonohydrazide (CAS 890522-64-2)
- 2-(1-(Tert-butoxycarbonyl)-3-hydroxypyrrolidin-3-yl)-2,2-difluoroacetic acid (CAS 1780822-41-4)
- 5-Iodo-2-methylnicotinaldehyde (CAS 1289071-76-6)
- [4-(3,5-dichlorophenoxy)phenyl]methanamine hydrochloride (CAS 1803582-98-0)
- 6,7-Dimethoxy-N-(2-nitrophenyl)quinazolin-4-amine (CAS 229476-52-2)
- D-Ala21-Tirzepatide (CAS CATO-CPTD788913)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com