Rupatadine Impurity 25 CAS 499-81-0
| CAS No. | 499-81-0 |
| Molecular Formula | C7H5NO4 |
| Molecular Weight | 167.12 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Rupatadine Impurity 25 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Rupatadine Impurity 25 (CAS 499-81-0, C7H5NO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C7H5NO4, Rupatadine Impurity 25 contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 167.12 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C7H5NO4 |
| Molecular Weight | 167.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Rupatadine Standards
- Rupatadine impurity 9 (CAS 41711-38-0)
- Rupatadine Impurity 23 (CAS 21636-51-1)
- Rupatadine Impurity 3 (CAS 102074-19-1)
- Rupatadine Impurity 24 (CAS 100910-66-5)
- Rupatadine Impurity 5 (CAS 35991-75-4)
- Rupatadine Impurity 36 (CAS 169253-15-0)
- Rupatadine Fumaric Acid (CAS 182349-12-8)
- Rupatadine impurity 1 (CAS 1118754-56-5)
Recommended Standards
- 73900-07-9 (~2~H_3_)Methyl trifluoromethanesulfonate DTXSID90583675 (CAS 73900-07-9)
- Moxifloxacin Impurity 91 (CAS 89-00-9)
- 5-Nitrobenzo[d][1,3]dioxole (CAS 2620-44-2)
- Nicotinic Acid EP Impurity D (CAS 100-26-5)
- Ambrisentan Impurity 4 (CAS 35144-22-0)
- Paliperidone Impurity 149 (CAS CATO-C4X-1724149)
- Selumetinib Impurity 15 (CAS CATO-C4X-305315)
- Benzyl ((1-(2-aminoethyl)piperidin-3-yl)methyl)(isopropyl)carbamate (CAS 1353967-91-5)
- 2-(Chloromethyl)-3-cyano-4-(difluoromethyl)pyridine-5-acetic acid (CAS 1806005-80-0)
- 3-(4-Methylphenyl)-1,2,5-oxadiazole (CAS 10349-07-2)
- 4-(4-Methoxyphenyl)-N-(2-methyl-4-nitrophenyl)thiazol-2-amine (CAS 685108-64-9)
- (5-Methoxy-3-(trifluoromethyl)pyridin-2-yl)methanamine (CAS 2770349-27-2)
- 3-((Phenylthio)methyl)piperidine hydrochloride (CAS 101798-82-7)
- Copper Peptide ·2 acetate salt (CAS 130120-57-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com