Bromhexine EP Impurity B CAS 50910-55-9
| CAS No. | 50910-55-9 |
| Molecular Formula | C7H5Br2NO |
| Molecular Weight | 278.93 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Bromhexine EP Impurity B (CAS 50910-55-9, C7H5Br2NO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Bromhexine EP Impurity B (C7H5Br2NO) contains an amide group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 278.93 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Bromhexine EP Impurity B under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H5Br2NO |
| Molecular Weight | 278.93 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromhexine Standards
- Bromhexine Impurity 23 (CAS 30273-41-7)
- Bromhexine Impurity N2 (CAS 63471-27-2)
- Bromhexine EP Impurity D (CAS 132004-28-5)
- Bromhexine Impurity 51 (CAS 100669-82-7)
- Bromhexine Impurity 34 (CAS 606-00-8)
- Bromhexine Impurity 38 (CAS CATO-C4X-106038)
- Bromhexine Impurity 7 (CAS 1631131-52-6)
- Bromhexine Related Compound 2 (CAS 32193-43-4)
Recommended Standards
- 4,6-Dibromopicolinimidamide (CAS 2089327-49-9)
- Ambroxol impurity 116 (CAS 1373889-89-4)
- 3,5-Dibromo-2-methylisonicotinaldehyde (CAS 2504230-92-4)
- Ambroxol Impurity 31 (CAS 42460-62-8)
- Fenofibrate Impurity 14 (CAS CATO-C4X-164314)
- Alogliptin impurity 76 (CAS 1353254-17-7（free base）)
- Iloperidone Impurity 7 (CAS CATO-C4X-16617)
- (4-Methyl-6-(methylamino)pyridin-3-yl)(phenyl)methanone (CAS 1355191-74-0)
- 1,2,3,4-tetrahydrobenzo(e)(1,4)diazepin-5-one (CAS 28544-83-4)
- 2-Chloro-N-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)acetamide (CAS 42458-71-9)
- (2E)-3-(3-Methoxyphenyl)-1-(3-nitrophenyl)prop-2-en-1-one (CAS 1321913-27-2)
- Darifenacin(acetic Acid) Des-(5-Ethyl-2,3-dihydrobenzofuran) (Darifenacin Impurity) (CAS 1050646-75-7)
- 3-(2-Aminoethyl)-5-Methoxy-1-Nitroso-1H-Indole-2-Carboxylic Acid (CAS CATO-C3D-26121)
- Liraglutide Impurity 20 TFA Salt (CAS CATO-C4X-199220)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com